A penta-component mpox mRNA vaccine induces protective immunity in nonhuman primates

A penta-component mpox mRNA vaccine induces protective immunity in nonhuman primates

Abstract The recent worldwide outbreaks of mpox prioritize the development of a safe and effective mRNA vaccine. The contemporary mpox virus (MPXV) exhibits changing virological and epidemiological features, notably affecting populations already vulnerable to human immunodeficiency virus (HIV). Here...

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Main Authors: Qing Ye, Dong Zhang, Rong-Rong Zhang, Qian Xu, Xing-Yao Huang, Baoying Huang, Meng-Xu Sun, Zhe Cong, Lin Zhu, Jianrong Ma, Na Li, Jingjing Zhang, Ting Chen, Jiahan Lu, Yongzhi Hou, Xiang Chen, Hai-Tao Liu, Chao Zhou, Rui-Ting Li, Mei Wu, Zheng-Jian Wang, Jiye Yin, Ye-Feng Qiu, Bo Ying, Wen-Jie Tan, Jing Xue, Cheng-Feng Qin
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54909-4
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