Generation, establishment and characterization of three pluripotent stem cell lines (CVTTHi002-A, CVTTHi003-A and CVTTHi004-A) from primary testicular somatic cells isolated from two prepuberal and one peripuberal Klinefelter Syndrome (47 XXY) patients

Generation, establishment and characterization of three pluripotent stem cell lines (CVTTHi002-A, CVTTHi003-A and CVTTHi004-A) from primary testicular somatic cells isolated from two prepuberal and one peripuberal Klinefelter Syndrome (47 XXY) patients

Klinefelter Syndrome (KS) is an aneuploid genetic condition in males characterized by at least one additional copy of the X chromosome. Due to fibrotic degeneration of the testis, these patients suffer infertility in the future. The pathogenic mechanism by which this occurs is still not well known....

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Main Authors: Myriam Martin-Inaraja, Irene Romayor, Andrea Sáez de Cámara, Lara Herrera, Ainhoa Palacios, Maria Villaverde, Silvia Santos, Miguel Ángel Vesga, Beatriz Barreña, Ana María Aransay, Juan Anguita, Estíbaliz Solorzano, María Begoña Prieto, Roberto Matorras, Cristina Eguizabal
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506125000078
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