Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery
Aim: Deficiencies in preoperative nutritional status increase the incidence of negative postoperative events. In this study, we aimed to investigate the effect of the prognostic nutrition index (PNI), neutrophil-to-lymphocyte (N/L) ratio, and C-reactive protein (CRP)-to-albumin (CRP/Alb) ratio on po...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2024-11-01
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| Series: | Haseki Tıp Bülteni |
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| Online Access: | https://www.hasekidergisi.com/articles/effects-of-prognostic-nutrition-index-neutrophillymphocyte-ratio-and-c-reactive-proteinalbumin-ratio-on-prognosis-undergoing-open-heart-surgery/doi/haseki.galenos.2024.9873 |
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| author | Anil Kilinc Nilay Tas Melih Urkmez Ebru Canakci Ilker Coskun Merve Elif Demirhan |
| author_facet | Anil Kilinc Nilay Tas Melih Urkmez Ebru Canakci Ilker Coskun Merve Elif Demirhan |
| author_sort | Anil Kilinc |
| collection | DOAJ |
| description | Aim: Deficiencies in preoperative nutritional status increase the incidence of negative postoperative events. In this study, we aimed to investigate the effect of the prognostic nutrition index (PNI), neutrophil-to-lymphocyte (N/L) ratio, and C-reactive protein (CRP)-to-albumin (CRP/Alb) ratio on postoperative prognosis in patients undergoing open-heart surgery.
Methods: Patients undergoing primary open-heart surgery in our hospital from December 2021 to August 2023 were screened for PNI, N/L ratio, and CRP/Alb ratios, along with durations in intensive care, total hospitalization, and 30-day mortality rates. Binary logistic regression and robust regression analyses were used for the statistical analysis of this cross-sectional study.
Results: The study included a total of 437 cases. All patients had a mean PNI of 49.35±7.70. A one-unit increase in PNI value reduced intensive care duration by 0.495 units (p=0.049), while it reduced discharge duration by 0.101 units (p<0.001). A one-unit reduction in PNI value increased mortality by 1.07 times (p=0.002). The other variables showed no significant effects on intensive care duration, total hospitalization, and 30-day mortality rates.
Conclusion: PNI, a marker of inflammatory and immune processes, may be a beneficial variable for estimating postoperative prognosis among patients undergoing open heart surgery. |
| format | Article |
| id | doaj-art-fa634e6fb7864a6b9ae77feb57a8c97e |
| institution | Kabale University |
| issn | 1302-0072 2147-2688 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj-art-fa634e6fb7864a6b9ae77feb57a8c97e2025-01-28T07:29:31ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882024-11-0162529530210.4274/haseki.galenos.2024.9873Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart SurgeryAnil Kilinc0https://orcid.org/0000-0003-4892-1266Nilay Tas1https://orcid.org/0000-0003-0472-2206Melih Urkmez2https://orcid.org/0000-0002-0961-6659Ebru Canakci3https://orcid.org/0000-0003-2093-9229Ilker Coskun4https://orcid.org/0000-0001-6781-3522Merve Elif Demirhan5https://orcid.org/0009-0003-1631-1727Ordu University Faculty of Medicine, Department of Anesthesiology and Reanimation, Ordu, TurkeyOrdu University Faculty of Medicine, Department of Anesthesiology and Reanimation, Ordu, TurkeyOrdu University Faculty of Medicine, Department of Cardiovascular Surgery, Ordu, TurkeyOrdu University Faculty of Medicine, Department of Anesthesiology and Reanimation, Ordu, TurkeyOrdu University Faculty of Medicine, Department of Anesthesiology and Reanimation, Ordu, TurkeyOrdu University Faculty of Medicine, Department of Anesthesiology and Reanimation, Ordu, TurkeyAim: Deficiencies in preoperative nutritional status increase the incidence of negative postoperative events. In this study, we aimed to investigate the effect of the prognostic nutrition index (PNI), neutrophil-to-lymphocyte (N/L) ratio, and C-reactive protein (CRP)-to-albumin (CRP/Alb) ratio on postoperative prognosis in patients undergoing open-heart surgery. Methods: Patients undergoing primary open-heart surgery in our hospital from December 2021 to August 2023 were screened for PNI, N/L ratio, and CRP/Alb ratios, along with durations in intensive care, total hospitalization, and 30-day mortality rates. Binary logistic regression and robust regression analyses were used for the statistical analysis of this cross-sectional study. Results: The study included a total of 437 cases. All patients had a mean PNI of 49.35±7.70. A one-unit increase in PNI value reduced intensive care duration by 0.495 units (p=0.049), while it reduced discharge duration by 0.101 units (p<0.001). A one-unit reduction in PNI value increased mortality by 1.07 times (p=0.002). The other variables showed no significant effects on intensive care duration, total hospitalization, and 30-day mortality rates. Conclusion: PNI, a marker of inflammatory and immune processes, may be a beneficial variable for estimating postoperative prognosis among patients undergoing open heart surgery.https://www.hasekidergisi.com/articles/effects-of-prognostic-nutrition-index-neutrophillymphocyte-ratio-and-c-reactive-proteinalbumin-ratio-on-prognosis-undergoing-open-heart-surgery/doi/haseki.galenos.2024.9873pnin/l ratiocrp/alb ratioopen-heart surgeryprognosis |
| spellingShingle | Anil Kilinc Nilay Tas Melih Urkmez Ebru Canakci Ilker Coskun Merve Elif Demirhan Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery Haseki Tıp Bülteni pni n/l ratio crp/alb ratio open-heart surgery prognosis |
| title | Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery |
| title_full | Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery |
| title_fullStr | Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery |
| title_full_unstemmed | Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery |
| title_short | Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery |
| title_sort | effects of prognostic nutrition index neutrophil lymphocyte ratio and c reactive protein albumin ratio on prognosis undergoing open heart surgery |
| topic | pni n/l ratio crp/alb ratio open-heart surgery prognosis |
| url | https://www.hasekidergisi.com/articles/effects-of-prognostic-nutrition-index-neutrophillymphocyte-ratio-and-c-reactive-proteinalbumin-ratio-on-prognosis-undergoing-open-heart-surgery/doi/haseki.galenos.2024.9873 |
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