Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery
Aim: Deficiencies in preoperative nutritional status increase the incidence of negative postoperative events. In this study, we aimed to investigate the effect of the prognostic nutrition index (PNI), neutrophil-to-lymphocyte (N/L) ratio, and C-reactive protein (CRP)-to-albumin (CRP/Alb) ratio on po...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2024-11-01
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| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: | https://www.hasekidergisi.com/articles/effects-of-prognostic-nutrition-index-neutrophillymphocyte-ratio-and-c-reactive-proteinalbumin-ratio-on-prognosis-undergoing-open-heart-surgery/doi/haseki.galenos.2024.9873 |
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| Summary: | Aim: Deficiencies in preoperative nutritional status increase the incidence of negative postoperative events. In this study, we aimed to investigate the effect of the prognostic nutrition index (PNI), neutrophil-to-lymphocyte (N/L) ratio, and C-reactive protein (CRP)-to-albumin (CRP/Alb) ratio on postoperative prognosis in patients undergoing open-heart surgery.
Methods: Patients undergoing primary open-heart surgery in our hospital from December 2021 to August 2023 were screened for PNI, N/L ratio, and CRP/Alb ratios, along with durations in intensive care, total hospitalization, and 30-day mortality rates. Binary logistic regression and robust regression analyses were used for the statistical analysis of this cross-sectional study.
Results: The study included a total of 437 cases. All patients had a mean PNI of 49.35±7.70. A one-unit increase in PNI value reduced intensive care duration by 0.495 units (p=0.049), while it reduced discharge duration by 0.101 units (p<0.001). A one-unit reduction in PNI value increased mortality by 1.07 times (p=0.002). The other variables showed no significant effects on intensive care duration, total hospitalization, and 30-day mortality rates.
Conclusion: PNI, a marker of inflammatory and immune processes, may be a beneficial variable for estimating postoperative prognosis among patients undergoing open heart surgery. |
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| ISSN: | 1302-0072 2147-2688 |