IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells

IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells

The inhibitory receptor interleukin-1 receptor 8 (IL-1R8) has been recently recognized to be expressed also by human natural killer (NK) cells. This study was aimed to design and optimize IL-1R8 silencing conditions in human NK cells to precisely establish the activity of such receptor in these cell...

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Main Authors: Enrico Maggi, Alberto Mantovani, Lorenzo Moretta, Francesca Romana Mariotti, Andrea Pelosi, Irene Veneziani, Claudia Alicata, Nadine Landolina, Biancamaria Ricci, Tiziano Ingegnere, Bruno Giuseppe Azzarone, Cecilia Garlanda
Format: Article
Language:English
Published: BMJ Publishing Group 2022-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/3/e003858.full
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https://jitc.bmj.com/content/10/3/e003858.full

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