Melatonin as a powerful antioxidant

Melatonin is a hormone that has many body functions and, for several decades, its antioxidant potential has been increasingly talked about. There is a relationship between failure in melatonin production in the pineal gland, an insufficient supply of this hormone to the body, and the occurrence of f...

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Main Authors: Chrustek Agnieszka, Olszewska-Słonina Dorota
Format: Article
Language:English
Published: Sciendo 2021-09-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2021-0027
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author Chrustek Agnieszka
Olszewska-Słonina Dorota
author_facet Chrustek Agnieszka
Olszewska-Słonina Dorota
author_sort Chrustek Agnieszka
collection DOAJ
description Melatonin is a hormone that has many body functions and, for several decades, its antioxidant potential has been increasingly talked about. There is a relationship between failure in melatonin production in the pineal gland, an insufficient supply of this hormone to the body, and the occurrence of free radical etiology diseases such as neurodegenerative diseases, cardiovascular diseases, diabetes, cancer and others. Despite the development of molecular biology, numerous in vitro and in vivo studies, the exact mechanism of melatonin antioxidant activity is still unknown. Nowadays, the use of melatonin supplementation is more and more common, not only to prevent insomnia, but also to slow down the aging process and provide protection against diseases. The aim of this study is to get acquainted with current reports on melatonin, antioxidative mechanisms and their importance in diseases of free radical etiology.
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series Acta Pharmaceutica
spelling doaj-art-fa30944977734f96baecd9e8f861768e2025-02-02T16:46:55ZengSciendoActa Pharmaceutica1846-95582021-09-0171333535410.2478/acph-2021-0027acph-2021-0027Melatonin as a powerful antioxidantChrustek Agnieszka0Olszewska-Słonina Dorota1Department of Pathobiochemistry and Clinical Chemistry, Faculty of Pharmacy, L. Rydygier Collegium Medicum Bydgoszcz, Nicolaus Copernicus University, Torun, PolandDepartment of Pathobiochemistry and Clinical Chemistry, Faculty of Pharmacy, L. Rydygier Collegium Medicum Bydgoszcz, Nicolaus Copernicus University, Torun, PolandMelatonin is a hormone that has many body functions and, for several decades, its antioxidant potential has been increasingly talked about. There is a relationship between failure in melatonin production in the pineal gland, an insufficient supply of this hormone to the body, and the occurrence of free radical etiology diseases such as neurodegenerative diseases, cardiovascular diseases, diabetes, cancer and others. Despite the development of molecular biology, numerous in vitro and in vivo studies, the exact mechanism of melatonin antioxidant activity is still unknown. Nowadays, the use of melatonin supplementation is more and more common, not only to prevent insomnia, but also to slow down the aging process and provide protection against diseases. The aim of this study is to get acquainted with current reports on melatonin, antioxidative mechanisms and their importance in diseases of free radical etiology.https://doi.org/10.2478/acph-2021-0027melatoninantioxidantslipid peroxidationfree radicalsoxidative stress
spellingShingle Chrustek Agnieszka
Olszewska-Słonina Dorota
Melatonin as a powerful antioxidant
Acta Pharmaceutica
melatonin
antioxidants
lipid peroxidation
free radicals
oxidative stress
title Melatonin as a powerful antioxidant
title_full Melatonin as a powerful antioxidant
title_fullStr Melatonin as a powerful antioxidant
title_full_unstemmed Melatonin as a powerful antioxidant
title_short Melatonin as a powerful antioxidant
title_sort melatonin as a powerful antioxidant
topic melatonin
antioxidants
lipid peroxidation
free radicals
oxidative stress
url https://doi.org/10.2478/acph-2021-0027
work_keys_str_mv AT chrustekagnieszka melatoninasapowerfulantioxidant
AT olszewskasłoninadorota melatoninasapowerfulantioxidant