Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients

Summary: Hypertension adversely affects glycolipid metabolism and vascular function in aging populations. This network meta-analysis evaluated 36 randomized trials (n = 2875) comparing traditional mind-body exercises (Tai Chi, Baduanjin, Daoyinyangshengshu) for metabolic and vascular improvements. A...

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Main Authors: Haojie Li, Xinyu Lin, Xinglu Li, Nan Chen, Xie Wu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225009435
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author Haojie Li
Xinyu Lin
Xinglu Li
Nan Chen
Xie Wu
author_facet Haojie Li
Xinyu Lin
Xinglu Li
Nan Chen
Xie Wu
author_sort Haojie Li
collection DOAJ
description Summary: Hypertension adversely affects glycolipid metabolism and vascular function in aging populations. This network meta-analysis evaluated 36 randomized trials (n = 2875) comparing traditional mind-body exercises (Tai Chi, Baduanjin, Daoyinyangshengshu) for metabolic and vascular improvements. Analyses revealed Tai Chi most effectively raised high-density lipoprotein (HDL) (standardized mean differences [SMD] = 0.88), while Daoyinyangshengshu optimally reduced fasting glucose (SMD = −1.21) and endothelin-1 (SMD = −1.82) while increasing nitric oxide (SMD = 1.41). Baduanjin best lowered low-density lipoprotein (LDL) (SMD = −0.95), with other exercises improving cholesterol and triglycerides. The findings demonstrate that specific mind-body practices differentially enhance cardiometabolic health, with Tai Chi and Daoyinyangshengshu showing particular promise for comprehensive benefits. These evidence-based results support incorporating traditional exercises into hypertension management protocols to address both metabolic and vascular dysfunction.
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spelling doaj-art-fa2c14b70b3b4166a64127df779da00a2025-08-20T02:17:04ZengElsevieriScience2589-00422025-06-0128611268210.1016/j.isci.2025.112682Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patientsHaojie Li0Xinyu Lin1Xinglu Li2Nan Chen3Xie Wu4School of Exercise and Health, Shanghai University of Sport, Shanghai, ChinaSchool of Exercise and Health, Shanghai University of Sport, Shanghai, ChinaSchool of Exercise and Health, Shanghai University of Sport, Shanghai, ChinaSchool of Exercise and Health, Shanghai University of Sport, Shanghai, China; Department of Rehabilitation, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China; Corresponding authorSchool of Exercise and Health, Shanghai University of Sport, Shanghai, China; Corresponding authorSummary: Hypertension adversely affects glycolipid metabolism and vascular function in aging populations. This network meta-analysis evaluated 36 randomized trials (n = 2875) comparing traditional mind-body exercises (Tai Chi, Baduanjin, Daoyinyangshengshu) for metabolic and vascular improvements. Analyses revealed Tai Chi most effectively raised high-density lipoprotein (HDL) (standardized mean differences [SMD] = 0.88), while Daoyinyangshengshu optimally reduced fasting glucose (SMD = −1.21) and endothelin-1 (SMD = −1.82) while increasing nitric oxide (SMD = 1.41). Baduanjin best lowered low-density lipoprotein (LDL) (SMD = −0.95), with other exercises improving cholesterol and triglycerides. The findings demonstrate that specific mind-body practices differentially enhance cardiometabolic health, with Tai Chi and Daoyinyangshengshu showing particular promise for comprehensive benefits. These evidence-based results support incorporating traditional exercises into hypertension management protocols to address both metabolic and vascular dysfunction.http://www.sciencedirect.com/science/article/pii/S2589004225009435Cardiovascular medicineKinesiology
spellingShingle Haojie Li
Xinyu Lin
Xinglu Li
Nan Chen
Xie Wu
Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients
iScience
Cardiovascular medicine
Kinesiology
title Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients
title_full Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients
title_fullStr Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients
title_full_unstemmed Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients
title_short Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients
title_sort effects of six chinese mind body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients
topic Cardiovascular medicine
Kinesiology
url http://www.sciencedirect.com/science/article/pii/S2589004225009435
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