CTLA-4 expression on tregs is needed for suppression of autoimmune uveitis

Abstract Uveitis is a leading cause of blindness in the world and autoimmune uveitis is an ocular tissue specific autoimmune disease. Utilizing experimental autoimmune uveitis (EAU), we can interrogate different immune responses in the mouse that are relevant to the human disease. cytotoxic T-lympho...

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Bibliographic Details
Main Authors: Minjun Ahn, John Dostal, Priya Hegde, Darren J. Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-02816-z
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