Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST).
<h4>Background</h4>The one-minute sit-to-stand-test (1-min STST) is a quick, space saving test to evaluate functional capacity. Exercise testing plays an important role in the long-term follow-up of pulmonary hypertension (PH) patients and is currently evaluated using the six-minute-walk...
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Public Library of Science (PLoS)
2023-01-01
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| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0282697&type=printable |
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| author | Christina Kronberger Roya Anahita Mousavi Begüm Öztürk Robin Willixhofer Theresa-Marie Dachs René Rettl Luciana Camuz-Ligios Nima Rassoulpour Christoph Krall Brigitte Litschauer Roza Badr Eslam |
| author_facet | Christina Kronberger Roya Anahita Mousavi Begüm Öztürk Robin Willixhofer Theresa-Marie Dachs René Rettl Luciana Camuz-Ligios Nima Rassoulpour Christoph Krall Brigitte Litschauer Roza Badr Eslam |
| author_sort | Christina Kronberger |
| collection | DOAJ |
| description | <h4>Background</h4>The one-minute sit-to-stand-test (1-min STST) is a quick, space saving test to evaluate functional capacity. Exercise testing plays an important role in the long-term follow-up of pulmonary hypertension (PH) patients and is currently evaluated using the six-minute-walk-test (6MWT). The aim of the study was to assess the convergent validity of the 1-min STST in patients with PH and its association with markers of PH severity.<h4>Methods</h4>We evaluated 106 PH patients with the 1-min-STST and 6MWT and measured cardiorespiratory parameters (heart rate, blood pressure, oxygen saturation) before and after test conduction. N-terminal pro brain-type natriuretic peptide (NT-proBNP), WHO functional class (WHO-FC) and mean pulmonary artery pressure (mPAP) were defined as markers of PH severity.<h4>Results</h4>Strong correlation was found between performances of 1-min STST and 6MWT (r = .711, p < .001), indicating convergent validity. Both tests were inversely associated with NT-proBNP (STST: r = -.405, p < .001; 6MWT: r = -.358, p < .001), WHO-FC (STST: r = -.591, p < .001; 6MWT: r = -.643, p < .001) and mPAP (STST: r = -.280, p < .001; 6MWT: r = -.250, p < .001). Significant changes in cardiorespiratory parameters were observed in both tests (all p < 0.001). Further the post-exercise cardiorespiratory parameters correlated strongly between the 1-min STST and 6MWT (all r ≥ .651, all p < .001).<h4>Conclusion</h4>The 1-min STST demonstrated good convergent validity with the 6MWT and was associated with markers of PH severity. Furthermore, both exercise tests caused similar cardiorespiratory responses. |
| format | Article |
| id | doaj-art-f9db15a7b3804fd6946fb4ac9b0c22a2 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj-art-f9db15a7b3804fd6946fb4ac9b0c22a22025-01-21T05:31:25ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01183e028269710.1371/journal.pone.0282697Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST).Christina KronbergerRoya Anahita MousaviBegüm ÖztürkRobin WillixhoferTheresa-Marie DachsRené RettlLuciana Camuz-LigiosNima RassoulpourChristoph KrallBrigitte LitschauerRoza Badr Eslam<h4>Background</h4>The one-minute sit-to-stand-test (1-min STST) is a quick, space saving test to evaluate functional capacity. Exercise testing plays an important role in the long-term follow-up of pulmonary hypertension (PH) patients and is currently evaluated using the six-minute-walk-test (6MWT). The aim of the study was to assess the convergent validity of the 1-min STST in patients with PH and its association with markers of PH severity.<h4>Methods</h4>We evaluated 106 PH patients with the 1-min-STST and 6MWT and measured cardiorespiratory parameters (heart rate, blood pressure, oxygen saturation) before and after test conduction. N-terminal pro brain-type natriuretic peptide (NT-proBNP), WHO functional class (WHO-FC) and mean pulmonary artery pressure (mPAP) were defined as markers of PH severity.<h4>Results</h4>Strong correlation was found between performances of 1-min STST and 6MWT (r = .711, p < .001), indicating convergent validity. Both tests were inversely associated with NT-proBNP (STST: r = -.405, p < .001; 6MWT: r = -.358, p < .001), WHO-FC (STST: r = -.591, p < .001; 6MWT: r = -.643, p < .001) and mPAP (STST: r = -.280, p < .001; 6MWT: r = -.250, p < .001). Significant changes in cardiorespiratory parameters were observed in both tests (all p < 0.001). Further the post-exercise cardiorespiratory parameters correlated strongly between the 1-min STST and 6MWT (all r ≥ .651, all p < .001).<h4>Conclusion</h4>The 1-min STST demonstrated good convergent validity with the 6MWT and was associated with markers of PH severity. Furthermore, both exercise tests caused similar cardiorespiratory responses.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0282697&type=printable |
| spellingShingle | Christina Kronberger Roya Anahita Mousavi Begüm Öztürk Robin Willixhofer Theresa-Marie Dachs René Rettl Luciana Camuz-Ligios Nima Rassoulpour Christoph Krall Brigitte Litschauer Roza Badr Eslam Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST). PLoS ONE |
| title | Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST). |
| title_full | Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST). |
| title_fullStr | Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST). |
| title_full_unstemmed | Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST). |
| title_short | Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST). |
| title_sort | functional capacity testing in patients with pulmonary hypertension ph using the one minute sit to stand test 1 min stst |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0282697&type=printable |
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