Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit Femur
This study aimed at investigating if a coating of hydroxyapatite nanocrystals would enhance bone healing over time in trabecular bone. Sandblasted and acid etched titanium implants with and without a submicron thick coat of hydroxyapatite nanocrystals (nano-HA) were implanted in rabbit femur with he...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2014/197581 |
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| author | Lory Melin Svanborg Luiz Meirelles Victoria Franke Stenport Per Kjellin Fredrik Currie Martin Andersson Ann Wennerberg |
| author_facet | Lory Melin Svanborg Luiz Meirelles Victoria Franke Stenport Per Kjellin Fredrik Currie Martin Andersson Ann Wennerberg |
| author_sort | Lory Melin Svanborg |
| collection | DOAJ |
| description | This study aimed at investigating if a coating of hydroxyapatite nanocrystals would enhance bone healing over time in trabecular bone. Sandblasted and acid etched titanium implants with and without a submicron thick coat of hydroxyapatite nanocrystals (nano-HA) were implanted in rabbit femur with healing times of 2, 4, and 9 weeks. Removal torque analyses and histological evaluations were performed. The torque analysis did not show any significant differences between the implants at any healing time. The control implant showed a tendency of more newly formed bone after 4 weeks of healing and significantly higher bone area values after 9 weeks of healing. According to the results from this present study, both control and nano-HA surfaces were biocompatible and osteoconductive. A submicron thick coating of hydroxyapatite nanocrystals deposited onto blasted and acid etched screw shaped titanium implants did not enhance bone healing, as compared to blasted and etched control implants when placed in trabecular bone. |
| format | Article |
| id | doaj-art-f9c2bcf8222548dbbd6c73578ff850da |
| institution | Kabale University |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-f9c2bcf8222548dbbd6c73578ff850da2025-02-03T01:11:02ZengWileyInternational Journal of Dentistry1687-87281687-87362014-01-01201410.1155/2014/197581197581Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit FemurLory Melin Svanborg0Luiz Meirelles1Victoria Franke Stenport2Per Kjellin3Fredrik Currie4Martin Andersson5Ann Wennerberg6Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö, SwedenDepartment of Biomaterials/Handicap Research, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, 405 30 Göteborg, SwedenDepartment of Prosthodontics/Dental Material Science, Institute of Odontology, Sahlgrenska Academy, Gothenburg University, 405 30 Göteborg, SwedenPromimic AB, 412 92 Göteborg, SwedenPromimic AB, 412 92 Göteborg, SwedenDepartment of Chemical and Biological Engineering, Applied Surface Chemistry, Chalmers University of Technology, 412 96 Göteborg, SwedenDepartment of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö, SwedenThis study aimed at investigating if a coating of hydroxyapatite nanocrystals would enhance bone healing over time in trabecular bone. Sandblasted and acid etched titanium implants with and without a submicron thick coat of hydroxyapatite nanocrystals (nano-HA) were implanted in rabbit femur with healing times of 2, 4, and 9 weeks. Removal torque analyses and histological evaluations were performed. The torque analysis did not show any significant differences between the implants at any healing time. The control implant showed a tendency of more newly formed bone after 4 weeks of healing and significantly higher bone area values after 9 weeks of healing. According to the results from this present study, both control and nano-HA surfaces were biocompatible and osteoconductive. A submicron thick coating of hydroxyapatite nanocrystals deposited onto blasted and acid etched screw shaped titanium implants did not enhance bone healing, as compared to blasted and etched control implants when placed in trabecular bone.http://dx.doi.org/10.1155/2014/197581 |
| spellingShingle | Lory Melin Svanborg Luiz Meirelles Victoria Franke Stenport Per Kjellin Fredrik Currie Martin Andersson Ann Wennerberg Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit Femur International Journal of Dentistry |
| title | Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit Femur |
| title_full | Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit Femur |
| title_fullStr | Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit Femur |
| title_full_unstemmed | Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit Femur |
| title_short | Evaluation of Bone Healing on Sandblasted and Acid Etched Implants Coated with Nanocrystalline Hydroxyapatite: An In Vivo Study in Rabbit Femur |
| title_sort | evaluation of bone healing on sandblasted and acid etched implants coated with nanocrystalline hydroxyapatite an in vivo study in rabbit femur |
| url | http://dx.doi.org/10.1155/2014/197581 |
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