Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder
22q11.2 deletion syndrome (22q11DS) is a risk factor for psychiatric illnesses, including schizophrenia and anxiety. Small studies have shown that several neuroleptic medications are effective in treating psychosis in this population, but are also associated with an increased risk of adverse effects...
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Wiley
2017-10-01
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Series: | Mental Illness |
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Online Access: | http://www.pagepress.org/journals/index.php/mi/article/view/7225 |
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author | Candace B. Borders Amanda Suzuki David Safani |
author_facet | Candace B. Borders Amanda Suzuki David Safani |
author_sort | Candace B. Borders |
collection | DOAJ |
description | 22q11.2 deletion syndrome (22q11DS) is a risk factor for psychiatric illnesses, including schizophrenia and anxiety. Small studies have shown that several neuroleptic medications are effective in treating psychosis in this population, but are also associated with an increased risk of adverse effects - particularly, seizures. In this case, we discuss a 34-year-old patient presenting with late onset schizophrenia, which ultimately led to her diagnosis of 22q11DS. Subsequent management of the patient’s psychosis with asenapine was complicated by concurrent anxiety and panic disorder; thus, we examine the role of anxiolytic therapy in conjunction with antipsychotics in this patient population. |
format | Article |
id | doaj-art-f9925d66d68b418385649f4803148102 |
institution | Kabale University |
issn | 2036-7457 2036-7465 |
language | English |
publishDate | 2017-10-01 |
publisher | Wiley |
record_format | Article |
series | Mental Illness |
spelling | doaj-art-f9925d66d68b418385649f48031481022025-02-03T05:58:01ZengWileyMental Illness2036-74572036-74652017-10-019210.4081/mi.2017.72253822Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorderCandace B. Borders0Amanda Suzuki1David Safani2University of California, Irvine, CAUniversity of California, Irvine, CAUniversity of California, Irvine, CA22q11.2 deletion syndrome (22q11DS) is a risk factor for psychiatric illnesses, including schizophrenia and anxiety. Small studies have shown that several neuroleptic medications are effective in treating psychosis in this population, but are also associated with an increased risk of adverse effects - particularly, seizures. In this case, we discuss a 34-year-old patient presenting with late onset schizophrenia, which ultimately led to her diagnosis of 22q11DS. Subsequent management of the patient’s psychosis with asenapine was complicated by concurrent anxiety and panic disorder; thus, we examine the role of anxiolytic therapy in conjunction with antipsychotics in this patient population.http://www.pagepress.org/journals/index.php/mi/article/view/722522q11.2 deletion syndrome, schizophrenia, anxiety, panic disorder, asenapine, clonazepam |
spellingShingle | Candace B. Borders Amanda Suzuki David Safani Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder Mental Illness 22q11.2 deletion syndrome, schizophrenia, anxiety, panic disorder, asenapine, clonazepam |
title | Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder |
title_full | Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder |
title_fullStr | Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder |
title_full_unstemmed | Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder |
title_short | Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder |
title_sort | treatment of 22q11 2 deletion syndrome associated schizophrenia with comorbid anxiety and panic disorder |
topic | 22q11.2 deletion syndrome, schizophrenia, anxiety, panic disorder, asenapine, clonazepam |
url | http://www.pagepress.org/journals/index.php/mi/article/view/7225 |
work_keys_str_mv | AT candacebborders treatmentof22q112deletionsyndromeassociatedschizophreniawithcomorbidanxietyandpanicdisorder AT amandasuzuki treatmentof22q112deletionsyndromeassociatedschizophreniawithcomorbidanxietyandpanicdisorder AT davidsafani treatmentof22q112deletionsyndromeassociatedschizophreniawithcomorbidanxietyandpanicdisorder |