Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder

22q11.2 deletion syndrome (22q11DS) is a risk factor for psychiatric illnesses, including schizophrenia and anxiety. Small studies have shown that several neuroleptic medications are effective in treating psychosis in this population, but are also associated with an increased risk of adverse effects...

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Main Authors: Candace B. Borders, Amanda Suzuki, David Safani
Format: Article
Language:English
Published: Wiley 2017-10-01
Series:Mental Illness
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/mi/article/view/7225
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author Candace B. Borders
Amanda Suzuki
David Safani
author_facet Candace B. Borders
Amanda Suzuki
David Safani
author_sort Candace B. Borders
collection DOAJ
description 22q11.2 deletion syndrome (22q11DS) is a risk factor for psychiatric illnesses, including schizophrenia and anxiety. Small studies have shown that several neuroleptic medications are effective in treating psychosis in this population, but are also associated with an increased risk of adverse effects - particularly, seizures. In this case, we discuss a 34-year-old patient presenting with late onset schizophrenia, which ultimately led to her diagnosis of 22q11DS. Subsequent management of the patient’s psychosis with asenapine was complicated by concurrent anxiety and panic disorder; thus, we examine the role of anxiolytic therapy in conjunction with antipsychotics in this patient population.
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series Mental Illness
spelling doaj-art-f9925d66d68b418385649f48031481022025-02-03T05:58:01ZengWileyMental Illness2036-74572036-74652017-10-019210.4081/mi.2017.72253822Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorderCandace B. Borders0Amanda Suzuki1David Safani2University of California, Irvine, CAUniversity of California, Irvine, CAUniversity of California, Irvine, CA22q11.2 deletion syndrome (22q11DS) is a risk factor for psychiatric illnesses, including schizophrenia and anxiety. Small studies have shown that several neuroleptic medications are effective in treating psychosis in this population, but are also associated with an increased risk of adverse effects - particularly, seizures. In this case, we discuss a 34-year-old patient presenting with late onset schizophrenia, which ultimately led to her diagnosis of 22q11DS. Subsequent management of the patient’s psychosis with asenapine was complicated by concurrent anxiety and panic disorder; thus, we examine the role of anxiolytic therapy in conjunction with antipsychotics in this patient population.http://www.pagepress.org/journals/index.php/mi/article/view/722522q11.2 deletion syndrome, schizophrenia, anxiety, panic disorder, asenapine, clonazepam
spellingShingle Candace B. Borders
Amanda Suzuki
David Safani
Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder
Mental Illness
22q11.2 deletion syndrome, schizophrenia, anxiety, panic disorder, asenapine, clonazepam
title Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder
title_full Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder
title_fullStr Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder
title_full_unstemmed Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder
title_short Treatment of 22q11.2 deletion syndrome-associated schizophrenia with comorbid anxiety and panic disorder
title_sort treatment of 22q11 2 deletion syndrome associated schizophrenia with comorbid anxiety and panic disorder
topic 22q11.2 deletion syndrome, schizophrenia, anxiety, panic disorder, asenapine, clonazepam
url http://www.pagepress.org/journals/index.php/mi/article/view/7225
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AT amandasuzuki treatmentof22q112deletionsyndromeassociatedschizophreniawithcomorbidanxietyandpanicdisorder
AT davidsafani treatmentof22q112deletionsyndromeassociatedschizophreniawithcomorbidanxietyandpanicdisorder