Effect of prednisolone on live birth rate in women with unexplained recurrent pregnancy loss: a study protocol for a double-blind, placebo-controlled, multicentre, randomised controlled trial (PREMI-study)

Effect of prednisolone on live birth rate in women with unexplained recurrent pregnancy loss: a study protocol for a double-blind, placebo-controlled, multicentre, randomised controlled trial (PREMI-study)

Introduction Recurrent pregnancy loss (RPL) is defined as the occurrence of two or more spontaneous pregnancy losses from the time of conception until 24 weeks of gestation. Currently, an underlying cause can be identified in only a minority of the losses. Potentially, an impaired maternal immune re...

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Main Authors: Saskia le Cessie, Nan van Geloven, Marie-Louise van der Hoorn, Michael Eikmans, Annemarie Mulders, Eileen Lashley, Jantien Visser, Moniek van der Zanden, Mariette Goddijn, Tess Meuleman, Salwan Al-Nasiry, Harold Verhoeve, Gijs Teklenburg, Jan-Peter de Bruin, Yentl Béquet, Renate Van der Molen, Elske van den Akker-van Marle, Marloes Vermeulen, Merel van den Berg, Astrid Cantineau, Dana Huppelschoten
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/6/e096545.full
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