Blastomyscosis Acquired by Three Children in Toronto
Three paediatric cases of blastomycosis, apparently acquired in or near Toronto, Ontario, a region not known to be endemic for this disease, are described. Blastomycosis was not suspected clinically in any of the three cases, and the diagnosis was established only when the diagnostic net was broaden...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2002-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2002/906757 |
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| _version_ | 1832565139440664576 |
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| author | Stacey Bernstein Hermine I Brunner Richard Summerbell Upton Allen Paul Babyn Susan E Richardson |
| author_facet | Stacey Bernstein Hermine I Brunner Richard Summerbell Upton Allen Paul Babyn Susan E Richardson |
| author_sort | Stacey Bernstein |
| collection | DOAJ |
| description | Three paediatric cases of blastomycosis, apparently acquired in or near Toronto, Ontario, a region not known to be endemic for this disease, are described. Blastomycosis was not suspected clinically in any of the three cases, and the diagnosis was established only when the diagnostic net was broadened to include fungal and mycobacterial cultures. All three patients were diagnosed after significant delays, which is consistent with the rarity of the disease in children and its acquisition outside previously accepted geographical boundaries. Pulmonary involvement was present in all three children, while one also had multifocal osteomyelitis. Drug therapy was successful in all three cases, either with amphotericin B followed by itraconazole, or itraconazole alone. Blastomycosis should be included in the differential diagnosis of a patient from the Toronto area who presents with a compatible history despite a negative travel history to known endemic zones. |
| format | Article |
| id | doaj-art-f979922124dd4205905444bd1eb07473 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 2002-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-f979922124dd4205905444bd1eb074732025-02-03T01:09:29ZengWileyCanadian Journal of Infectious Diseases1180-23322002-01-0113425926310.1155/2002/906757Blastomyscosis Acquired by Three Children in TorontoStacey Bernstein0Hermine I Brunner1Richard Summerbell2Upton Allen3Paul Babyn4Susan E Richardson5Department of Paediatrics, The Hospital for Sick Children, Toronto, CanadaDepartment of Paediatrics, The Hospital for Sick Children, Toronto, CanadaLaboratory Branch, Ontario Ministry of Health and Long Term Care, CanadaDepartment of Paediatrics, The Hospital for Sick Children, Toronto, CanadaDepartment of Radiology, The Hospital for Sick Children, Toronto, CanadaPaediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, CanadaThree paediatric cases of blastomycosis, apparently acquired in or near Toronto, Ontario, a region not known to be endemic for this disease, are described. Blastomycosis was not suspected clinically in any of the three cases, and the diagnosis was established only when the diagnostic net was broadened to include fungal and mycobacterial cultures. All three patients were diagnosed after significant delays, which is consistent with the rarity of the disease in children and its acquisition outside previously accepted geographical boundaries. Pulmonary involvement was present in all three children, while one also had multifocal osteomyelitis. Drug therapy was successful in all three cases, either with amphotericin B followed by itraconazole, or itraconazole alone. Blastomycosis should be included in the differential diagnosis of a patient from the Toronto area who presents with a compatible history despite a negative travel history to known endemic zones.http://dx.doi.org/10.1155/2002/906757 |
| spellingShingle | Stacey Bernstein Hermine I Brunner Richard Summerbell Upton Allen Paul Babyn Susan E Richardson Blastomyscosis Acquired by Three Children in Toronto Canadian Journal of Infectious Diseases |
| title | Blastomyscosis Acquired by Three Children in Toronto |
| title_full | Blastomyscosis Acquired by Three Children in Toronto |
| title_fullStr | Blastomyscosis Acquired by Three Children in Toronto |
| title_full_unstemmed | Blastomyscosis Acquired by Three Children in Toronto |
| title_short | Blastomyscosis Acquired by Three Children in Toronto |
| title_sort | blastomyscosis acquired by three children in toronto |
| url | http://dx.doi.org/10.1155/2002/906757 |
| work_keys_str_mv | AT staceybernstein blastomyscosisacquiredbythreechildrenintoronto AT hermineibrunner blastomyscosisacquiredbythreechildrenintoronto AT richardsummerbell blastomyscosisacquiredbythreechildrenintoronto AT uptonallen blastomyscosisacquiredbythreechildrenintoronto AT paulbabyn blastomyscosisacquiredbythreechildrenintoronto AT susanerichardson blastomyscosisacquiredbythreechildrenintoronto |