Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects

The rise in antimicrobial resistance is a cause of serious concern since the ages. Therefore, a dire need to explore new antimicrobial entities that can combat against the increasing threat of antibiotic resistance is realized. Studies have shown that the activity of the strongest antibiotics has re...

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Main Authors: Bharti Sharma, Sudeep Shukla, Rohit Rattan, Musarrat Fatima, Mayurika Goel, Mamta Bhat, Shruti Dutta, Rakesh Kumar Ranjan, Mamta Sharma
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2022/6819080
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author Bharti Sharma
Sudeep Shukla
Rohit Rattan
Musarrat Fatima
Mayurika Goel
Mamta Bhat
Shruti Dutta
Rakesh Kumar Ranjan
Mamta Sharma
author_facet Bharti Sharma
Sudeep Shukla
Rohit Rattan
Musarrat Fatima
Mayurika Goel
Mamta Bhat
Shruti Dutta
Rakesh Kumar Ranjan
Mamta Sharma
author_sort Bharti Sharma
collection DOAJ
description The rise in antimicrobial resistance is a cause of serious concern since the ages. Therefore, a dire need to explore new antimicrobial entities that can combat against the increasing threat of antibiotic resistance is realized. Studies have shown that the activity of the strongest antibiotics has reduced drastically against many microbes such as microfungi and bacteria (Gram-positive and Gram-negative). A ray of hope, however, was witnessed in early 1940s with the development of new drug discovery and use of metal complexes as antibiotics. Many new metal-based drugs were developed from the metal complexes which are potentially active against a number of ailments such as cancer, malaria, and neurodegenerative diseases. Therefore, this review is an attempt to describe the present scenario and future development of metal complexes as antibiotics against wide array of microbes.
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institution Kabale University
issn 1687-8795
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publishDate 2022-01-01
publisher Wiley
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series International Journal of Biomaterials
spelling doaj-art-f96ce6423c0b4b4989bbea26117b2fbd2025-02-03T05:57:26ZengWileyInternational Journal of Biomaterials1687-87952022-01-01202210.1155/2022/6819080Antimicrobial Agents Based on Metal Complexes: Present Situation and Future ProspectsBharti Sharma0Sudeep Shukla1Rohit Rattan2Musarrat Fatima3Mayurika Goel4Mamta Bhat5Shruti Dutta6Rakesh Kumar Ranjan7Mamta Sharma8School of Biosciences and BiotechnologyEnvironment Pollution Analysis LabWWF-India Field OfficeDepartment of BotanyTERI Deakin Nanobiotechnology CentreSchool of Biosciences and BiotechnologyAmity School of Earth and Environmental SciencesDepartment of GeologyAditi MahavidyalayaThe rise in antimicrobial resistance is a cause of serious concern since the ages. Therefore, a dire need to explore new antimicrobial entities that can combat against the increasing threat of antibiotic resistance is realized. Studies have shown that the activity of the strongest antibiotics has reduced drastically against many microbes such as microfungi and bacteria (Gram-positive and Gram-negative). A ray of hope, however, was witnessed in early 1940s with the development of new drug discovery and use of metal complexes as antibiotics. Many new metal-based drugs were developed from the metal complexes which are potentially active against a number of ailments such as cancer, malaria, and neurodegenerative diseases. Therefore, this review is an attempt to describe the present scenario and future development of metal complexes as antibiotics against wide array of microbes.http://dx.doi.org/10.1155/2022/6819080
spellingShingle Bharti Sharma
Sudeep Shukla
Rohit Rattan
Musarrat Fatima
Mayurika Goel
Mamta Bhat
Shruti Dutta
Rakesh Kumar Ranjan
Mamta Sharma
Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects
International Journal of Biomaterials
title Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects
title_full Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects
title_fullStr Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects
title_full_unstemmed Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects
title_short Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects
title_sort antimicrobial agents based on metal complexes present situation and future prospects
url http://dx.doi.org/10.1155/2022/6819080
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