Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects
The rise in antimicrobial resistance is a cause of serious concern since the ages. Therefore, a dire need to explore new antimicrobial entities that can combat against the increasing threat of antibiotic resistance is realized. Studies have shown that the activity of the strongest antibiotics has re...
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Format: | Article |
Language: | English |
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Wiley
2022-01-01
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Series: | International Journal of Biomaterials |
Online Access: | http://dx.doi.org/10.1155/2022/6819080 |
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author | Bharti Sharma Sudeep Shukla Rohit Rattan Musarrat Fatima Mayurika Goel Mamta Bhat Shruti Dutta Rakesh Kumar Ranjan Mamta Sharma |
author_facet | Bharti Sharma Sudeep Shukla Rohit Rattan Musarrat Fatima Mayurika Goel Mamta Bhat Shruti Dutta Rakesh Kumar Ranjan Mamta Sharma |
author_sort | Bharti Sharma |
collection | DOAJ |
description | The rise in antimicrobial resistance is a cause of serious concern since the ages. Therefore, a dire need to explore new antimicrobial entities that can combat against the increasing threat of antibiotic resistance is realized. Studies have shown that the activity of the strongest antibiotics has reduced drastically against many microbes such as microfungi and bacteria (Gram-positive and Gram-negative). A ray of hope, however, was witnessed in early 1940s with the development of new drug discovery and use of metal complexes as antibiotics. Many new metal-based drugs were developed from the metal complexes which are potentially active against a number of ailments such as cancer, malaria, and neurodegenerative diseases. Therefore, this review is an attempt to describe the present scenario and future development of metal complexes as antibiotics against wide array of microbes. |
format | Article |
id | doaj-art-f96ce6423c0b4b4989bbea26117b2fbd |
institution | Kabale University |
issn | 1687-8795 |
language | English |
publishDate | 2022-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Biomaterials |
spelling | doaj-art-f96ce6423c0b4b4989bbea26117b2fbd2025-02-03T05:57:26ZengWileyInternational Journal of Biomaterials1687-87952022-01-01202210.1155/2022/6819080Antimicrobial Agents Based on Metal Complexes: Present Situation and Future ProspectsBharti Sharma0Sudeep Shukla1Rohit Rattan2Musarrat Fatima3Mayurika Goel4Mamta Bhat5Shruti Dutta6Rakesh Kumar Ranjan7Mamta Sharma8School of Biosciences and BiotechnologyEnvironment Pollution Analysis LabWWF-India Field OfficeDepartment of BotanyTERI Deakin Nanobiotechnology CentreSchool of Biosciences and BiotechnologyAmity School of Earth and Environmental SciencesDepartment of GeologyAditi MahavidyalayaThe rise in antimicrobial resistance is a cause of serious concern since the ages. Therefore, a dire need to explore new antimicrobial entities that can combat against the increasing threat of antibiotic resistance is realized. Studies have shown that the activity of the strongest antibiotics has reduced drastically against many microbes such as microfungi and bacteria (Gram-positive and Gram-negative). A ray of hope, however, was witnessed in early 1940s with the development of new drug discovery and use of metal complexes as antibiotics. Many new metal-based drugs were developed from the metal complexes which are potentially active against a number of ailments such as cancer, malaria, and neurodegenerative diseases. Therefore, this review is an attempt to describe the present scenario and future development of metal complexes as antibiotics against wide array of microbes.http://dx.doi.org/10.1155/2022/6819080 |
spellingShingle | Bharti Sharma Sudeep Shukla Rohit Rattan Musarrat Fatima Mayurika Goel Mamta Bhat Shruti Dutta Rakesh Kumar Ranjan Mamta Sharma Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects International Journal of Biomaterials |
title | Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects |
title_full | Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects |
title_fullStr | Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects |
title_full_unstemmed | Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects |
title_short | Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects |
title_sort | antimicrobial agents based on metal complexes present situation and future prospects |
url | http://dx.doi.org/10.1155/2022/6819080 |
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