Orally administered live BCG and heat-inactivated Mycobacterium bovis protect bison against experimental bovine tuberculosis

Orally administered live BCG and heat-inactivated Mycobacterium bovis protect bison against experimental bovine tuberculosis

Abstract Bovine tuberculosis (BTB) is an infectious disease of livestock and wildlife species that is caused by pathogenic members of the Mycobacterium tuberculosis complex such as Mycobacterium bovis. Due to the introduction of M. bovis-infected bison in the 1920s, BTB is now endemic in wood bison...

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Bibliographic Details
Main Authors: Nirajan Niroula, Priya Ghodasara, Nelson Marreros, Bailey Fuller, Haley Sanderson, Slim Zriba, Stew Walker, Todd K. Shury, Jeffrey M. Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Bison
Bovine TB
Heat Inactivated Vaccine
Live BCG
DIVA
Online Access:https://doi.org/10.1038/s41598-025-88176-0
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