Rare e14a3 (b3a3) BCR-ABL Fusion in Chronic Myeloid Leukemia in India: The Threats and Challenges in Monitoring Minimal Residual Disease (MRD)
Objective: The primary objective of this work was to confirm the occurrence of rare BCR ABL fusion variant involving the a3 region of the ABL gene in a patient positive for t(9;22) translocation but negative for common major and minor breakpoint cluster regions and the challenges and threats that it...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.3233/ACP-130083 |
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| _version_ | 1832568470208774144 |
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| author | Salil Vaniawala Arpan Acharya Harsh Parekh Pratap N. Mukhopadhyaya |
| author_facet | Salil Vaniawala Arpan Acharya Harsh Parekh Pratap N. Mukhopadhyaya |
| author_sort | Salil Vaniawala |
| collection | DOAJ |
| description | Objective: The primary objective of this work was to confirm the occurrence of rare BCR ABL fusion variant involving the a3 region of the ABL gene in a patient positive for t(9;22) translocation but negative for common major and minor breakpoint cluster regions and the challenges and threats that it poses in a routine laboratory setting which use commercial kits for monitoring the minimal residual disease. |
| format | Article |
| id | doaj-art-f9475748fe564f78a481cac5f2e909f9 |
| institution | Kabale University |
| issn | 2210-7177 2210-7185 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-f9475748fe564f78a481cac5f2e909f92025-02-03T00:59:00ZengWileyAnalytical Cellular Pathology2210-71772210-71852013-01-01363-4859210.3233/ACP-130083Rare e14a3 (b3a3) BCR-ABL Fusion in Chronic Myeloid Leukemia in India: The Threats and Challenges in Monitoring Minimal Residual Disease (MRD)Salil Vaniawala0Arpan Acharya1Harsh Parekh2Pratap N. Mukhopadhyaya3SN Genelab, Surat, Gujarat, IndiaDr. D. Y. Patil Biotechnology & Bioinformatics Institute, Tathawade, Pune, IndiaInterdisciplinary Science, Technology and Research Academy, AISC, New Modhikana, Katad Khana, Pune, IndiaInterdisciplinary Science, Technology and Research Academy, AISC, New Modhikana, Katad Khana, Pune, IndiaObjective: The primary objective of this work was to confirm the occurrence of rare BCR ABL fusion variant involving the a3 region of the ABL gene in a patient positive for t(9;22) translocation but negative for common major and minor breakpoint cluster regions and the challenges and threats that it poses in a routine laboratory setting which use commercial kits for monitoring the minimal residual disease.http://dx.doi.org/10.3233/ACP-130083 |
| spellingShingle | Salil Vaniawala Arpan Acharya Harsh Parekh Pratap N. Mukhopadhyaya Rare e14a3 (b3a3) BCR-ABL Fusion in Chronic Myeloid Leukemia in India: The Threats and Challenges in Monitoring Minimal Residual Disease (MRD) Analytical Cellular Pathology |
| title | Rare e14a3 (b3a3) BCR-ABL Fusion in Chronic Myeloid Leukemia in India: The Threats and Challenges in Monitoring Minimal Residual Disease (MRD) |
| title_full | Rare e14a3 (b3a3) BCR-ABL Fusion in Chronic Myeloid Leukemia in India: The Threats and Challenges in Monitoring Minimal Residual Disease (MRD) |
| title_fullStr | Rare e14a3 (b3a3) BCR-ABL Fusion in Chronic Myeloid Leukemia in India: The Threats and Challenges in Monitoring Minimal Residual Disease (MRD) |
| title_full_unstemmed | Rare e14a3 (b3a3) BCR-ABL Fusion in Chronic Myeloid Leukemia in India: The Threats and Challenges in Monitoring Minimal Residual Disease (MRD) |
| title_short | Rare e14a3 (b3a3) BCR-ABL Fusion in Chronic Myeloid Leukemia in India: The Threats and Challenges in Monitoring Minimal Residual Disease (MRD) |
| title_sort | rare e14a3 b3a3 bcr abl fusion in chronic myeloid leukemia in india the threats and challenges in monitoring minimal residual disease mrd |
| url | http://dx.doi.org/10.3233/ACP-130083 |
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