Alice in Wonderland Syndrome: Localising insights from right visual cortex stroke complicated by epilepsia partialis continua

The Alice in Wonderland syndrome comprises visual and/or somaesthetic distortions, most often migrainous in origin. We present a case of Alice in Wonderland syndrome in association with a right posterior/visual cortex infarction with subsequent seizures including focal motor status (epilepsia partia...

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Main Authors: Gashirai K. Mbizvo, Viraj Bharambe, Brython Hywel, Shubhabrata Biswas, Andrew J. Larner
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Epilepsy & Behavior Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S258998642500005X
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author Gashirai K. Mbizvo
Viraj Bharambe
Brython Hywel
Shubhabrata Biswas
Andrew J. Larner
author_facet Gashirai K. Mbizvo
Viraj Bharambe
Brython Hywel
Shubhabrata Biswas
Andrew J. Larner
author_sort Gashirai K. Mbizvo
collection DOAJ
description The Alice in Wonderland syndrome comprises visual and/or somaesthetic distortions, most often migrainous in origin. We present a case of Alice in Wonderland syndrome in association with a right posterior/visual cortex infarction with subsequent seizures including focal motor status (epilepsia partialis continua), the latter a hitherto unreported association. These pathophysiological changes were of right hemisphere origin, suggesting Alice in Wonderland syndrome, if present, might have localising value for seizure focus in the right hemisphere.
format Article
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institution Kabale University
issn 2589-9864
language English
publishDate 2025-03-01
publisher Elsevier
record_format Article
series Epilepsy & Behavior Reports
spelling doaj-art-f937ee8e2a12403db219a75110b111362025-02-04T04:10:32ZengElsevierEpilepsy & Behavior Reports2589-98642025-03-0129100745Alice in Wonderland Syndrome: Localising insights from right visual cortex stroke complicated by epilepsia partialis continuaGashirai K. Mbizvo0Viraj Bharambe1Brython Hywel2Shubhabrata Biswas3Andrew J. Larner4Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, United Kingdom; Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom; Neurology Department, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom; Corresponding author at: Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7BE, United KingdomNeurology Department, The Walton Centre NHS Foundation Trust, Liverpool, United KingdomNeurophysiology Department, The Walton Centre NHS Foundation Trust, Liverpool, United KingdomNeuroradiology Department, The Walton Centre NHS Foundation Trust, Liverpool, United KingdomDepartment of Brain Repair & Rehabilitation, Institute of Neurology, University College London, London, United KingdomThe Alice in Wonderland syndrome comprises visual and/or somaesthetic distortions, most often migrainous in origin. We present a case of Alice in Wonderland syndrome in association with a right posterior/visual cortex infarction with subsequent seizures including focal motor status (epilepsia partialis continua), the latter a hitherto unreported association. These pathophysiological changes were of right hemisphere origin, suggesting Alice in Wonderland syndrome, if present, might have localising value for seizure focus in the right hemisphere.http://www.sciencedirect.com/science/article/pii/S258998642500005XSyndrome of distorted perceptionStatus epilepticusMyoclonusCerebral infarctCerebrovascular disease
spellingShingle Gashirai K. Mbizvo
Viraj Bharambe
Brython Hywel
Shubhabrata Biswas
Andrew J. Larner
Alice in Wonderland Syndrome: Localising insights from right visual cortex stroke complicated by epilepsia partialis continua
Epilepsy & Behavior Reports
Syndrome of distorted perception
Status epilepticus
Myoclonus
Cerebral infarct
Cerebrovascular disease
title Alice in Wonderland Syndrome: Localising insights from right visual cortex stroke complicated by epilepsia partialis continua
title_full Alice in Wonderland Syndrome: Localising insights from right visual cortex stroke complicated by epilepsia partialis continua
title_fullStr Alice in Wonderland Syndrome: Localising insights from right visual cortex stroke complicated by epilepsia partialis continua
title_full_unstemmed Alice in Wonderland Syndrome: Localising insights from right visual cortex stroke complicated by epilepsia partialis continua
title_short Alice in Wonderland Syndrome: Localising insights from right visual cortex stroke complicated by epilepsia partialis continua
title_sort alice in wonderland syndrome localising insights from right visual cortex stroke complicated by epilepsia partialis continua
topic Syndrome of distorted perception
Status epilepticus
Myoclonus
Cerebral infarct
Cerebrovascular disease
url http://www.sciencedirect.com/science/article/pii/S258998642500005X
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