Study on the role of activation of TGF-β pathway by ASPN in the occurrence and development of keloid and the underlying mechanisms

Study on the role of activation of TGF-β pathway by ASPN in the occurrence and development of keloid and the underlying mechanisms

[Objective] To investigate the role of ASPN in the development of keloid and the underlying mechanisms. [Methods] Immunofluorescence staining was used to assess the expression levels of ASPN in keloid of keloid patients and normal scar. WB and qRT-PCR were used to assess the activity of TGF-β pathwa...

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Bibliographic Details
Main Authors: XU Xueyan, CHEN Junyi, YAO Liuyi, DENG Chengcheng
Format: Article
Language:zho
Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology 2025-01-01
Series:Pifu-xingbing zhenliaoxue zazhi
Subjects:
keloid
aspn protein
tgf-β pathway
collagen
postn protein
Online Access:http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.01.002
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