The Interaction of Src Kinase with β3 Integrin Tails: A Potential Therapeutic Target in Thrombosis and Cancer
Activation of Src family kinases is an important event downstream of integrin adhesion signaling in many cell types. A particularly intriguing connection between an integrin and a Src family kinase was first discovered in platelets, where the selective direct interaction of αIIbβ3 integrins with c-S...
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Main Authors: | Stephan Huveneers, Erik H. J. Danen |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1100/tsw.2010.114 |
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