Patient perspective on symptoms of Notalgia paresthetica: subpopulation results from the Neuropathic Itch Patient Survey (NIRVE)

Background: Notalgia paresthetica (NP) is a form of neuropathic itch characterized by recurrent itch in the mid back. Much about NP remains unclear, especially the patient experience.Objectives: The Neuropathic Itch Patient Survey (NIRVE) was a global, online survey conducted to better characterize...

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Main Authors: Brian S. Kim, Jennifer A. Mohawk, Sherri So, Joshua Cirulli, Joana Goncalves, Joseph C. Punzalan, Mark Lebwohl
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Dermatological Treatment
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Online Access:https://www.tandfonline.com/doi/10.1080/09546634.2024.2394107
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author Brian S. Kim
Jennifer A. Mohawk
Sherri So
Joshua Cirulli
Joana Goncalves
Joseph C. Punzalan
Mark Lebwohl
author_facet Brian S. Kim
Jennifer A. Mohawk
Sherri So
Joshua Cirulli
Joana Goncalves
Joseph C. Punzalan
Mark Lebwohl
author_sort Brian S. Kim
collection DOAJ
description Background: Notalgia paresthetica (NP) is a form of neuropathic itch characterized by recurrent itch in the mid back. Much about NP remains unclear, especially the patient experience.Objectives: The Neuropathic Itch Patient Survey (NIRVE) was a global, online survey conducted to better characterize the symptom burden of neuropathic itch from the patient perspective.Patients and methods: This report focuses on the symptom burden of the subpopulation of NIRVE participants with a self-reported diagnosis of NP (N = 91). Respondents reported visiting a median of 2 healthcare providers (HCPs) for their symptoms before receiving an accurate diagnosis of NP.Results: The most common cutaneous symptoms ever experienced were itch/pruritus, sensitive skin, painful or raw skin, numbness, and tingling. The symptoms reported by the most respondents as currently being experienced included itch/pruritus, numbness, painful or raw skin, tingling, and burning or hot sensation. Of patients currently experiencing symptoms, numbness and itch/pruritus were ranked as the most intense, followed by tingling, burning or hot sensation, and then painful or raw skin. Most patients consult multiple healthcare providers (HCPs) before receiving a diagnosis for their condition.Conclusion: Itch is overwhelmingly the most prevalent symptom of the condition, although half of patients also report experiencing sensitive skin, painful or raw skin, numbness, or tingling.
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spelling doaj-art-f9214dd5bf8e490b9af8d603aaddb8322025-08-20T02:36:35ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532024-12-0135110.1080/09546634.2024.2394107Patient perspective on symptoms of Notalgia paresthetica: subpopulation results from the Neuropathic Itch Patient Survey (NIRVE)Brian S. Kim0Jennifer A. Mohawk1Sherri So2Joshua Cirulli3Joana Goncalves4Joseph C. Punzalan5Mark Lebwohl6Kimberly and Eric J. Waldman Department of Dermatology, Mark Lebwohl Center for Neuroinflammation and Sensation, Marc and Jennifer Lipschultz Precision Immunology Institute, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USACara Therapeutics, Inc, Stamford, CT, USACara Therapeutics, Inc, Stamford, CT, USACara Therapeutics, Inc, Stamford, CT, USACara Therapeutics, Inc, Stamford, CT, USAAplusA Bell Falla, LLC, Newark, NJ, USAKimberly and Eric J. Waldman Department of Dermatology, Mark Lebwohl Center for Neuroinflammation and Sensation, Marc and Jennifer Lipschultz Precision Immunology Institute, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USABackground: Notalgia paresthetica (NP) is a form of neuropathic itch characterized by recurrent itch in the mid back. Much about NP remains unclear, especially the patient experience.Objectives: The Neuropathic Itch Patient Survey (NIRVE) was a global, online survey conducted to better characterize the symptom burden of neuropathic itch from the patient perspective.Patients and methods: This report focuses on the symptom burden of the subpopulation of NIRVE participants with a self-reported diagnosis of NP (N = 91). Respondents reported visiting a median of 2 healthcare providers (HCPs) for their symptoms before receiving an accurate diagnosis of NP.Results: The most common cutaneous symptoms ever experienced were itch/pruritus, sensitive skin, painful or raw skin, numbness, and tingling. The symptoms reported by the most respondents as currently being experienced included itch/pruritus, numbness, painful or raw skin, tingling, and burning or hot sensation. Of patients currently experiencing symptoms, numbness and itch/pruritus were ranked as the most intense, followed by tingling, burning or hot sensation, and then painful or raw skin. Most patients consult multiple healthcare providers (HCPs) before receiving a diagnosis for their condition.Conclusion: Itch is overwhelmingly the most prevalent symptom of the condition, although half of patients also report experiencing sensitive skin, painful or raw skin, numbness, or tingling.https://www.tandfonline.com/doi/10.1080/09546634.2024.2394107Notalgia parestheticapruritusneuropathic itchsensory neuropathypatient survey
spellingShingle Brian S. Kim
Jennifer A. Mohawk
Sherri So
Joshua Cirulli
Joana Goncalves
Joseph C. Punzalan
Mark Lebwohl
Patient perspective on symptoms of Notalgia paresthetica: subpopulation results from the Neuropathic Itch Patient Survey (NIRVE)
Journal of Dermatological Treatment
Notalgia paresthetica
pruritus
neuropathic itch
sensory neuropathy
patient survey
title Patient perspective on symptoms of Notalgia paresthetica: subpopulation results from the Neuropathic Itch Patient Survey (NIRVE)
title_full Patient perspective on symptoms of Notalgia paresthetica: subpopulation results from the Neuropathic Itch Patient Survey (NIRVE)
title_fullStr Patient perspective on symptoms of Notalgia paresthetica: subpopulation results from the Neuropathic Itch Patient Survey (NIRVE)
title_full_unstemmed Patient perspective on symptoms of Notalgia paresthetica: subpopulation results from the Neuropathic Itch Patient Survey (NIRVE)
title_short Patient perspective on symptoms of Notalgia paresthetica: subpopulation results from the Neuropathic Itch Patient Survey (NIRVE)
title_sort patient perspective on symptoms of notalgia paresthetica subpopulation results from the neuropathic itch patient survey nirve
topic Notalgia paresthetica
pruritus
neuropathic itch
sensory neuropathy
patient survey
url https://www.tandfonline.com/doi/10.1080/09546634.2024.2394107
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