Novel, low-cost bioreactor for in vitro electrical stimulation of cardiac cells

Novel, low-cost bioreactor for in vitro electrical stimulation of cardiac cells

IntroductionThe successful implantation of laboratory-grown cardiac tissue requires phenotypically mature cardiomyocytes capable of electrophysiological integration with native heart tissue. Pulsed electrical stimulation (ES) has been identified as a promising strategy for enhancing cardiomyocyte ma...

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Bibliographic Details
Main Authors: Joseph P. Licata, Jonathan A. Gerstenhaber, Peter I. Lelkes
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
stem cells
organoids
computational modeling
3D printing
cardiomyocyte
electric field modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1531731/full
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