Transcriptome analysis and reverse engineering verification of SNZ3Val125Ile and Pho3Asn134Asp revealed the mechanism of adaptive laboratory evolution to increase the yield of tyrosol in Saccharomyces cerevisiae strain S26-AE2

Abstract Background Tyrosol is an important drug precursor, and Saccharomyces cerevisiae is one of the main microorganisms that produces tyrosol. Although excessive metabolic modification increases the production of tyrosol, it also causes a decrease in the growth rate of yeast. Therefore, this stud...

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Bibliographic Details
Main Authors: Na Song, Huili Xia, Xiaoxue Yang, Siyao Liu, Linglong Xu, Kun Zhuang, Lan Yao, Shihui Yang, Xiong Chen, Jun Dai
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Biotechnology for Biofuels and Bioproducts
Online Access:https://doi.org/10.1186/s13068-025-02627-4
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