Quality of Evidence Supporting the Role of Supplement Curcumin for the Treatment of Ulcerative Colitis: An Overview of Systematic Reviews
Objectives. Curcumin is a potential complementary treatment for ulcerative colitis (UC). This overview systematically summarizes and evaluates the existing evidence of curcumin in the treatment of UC. Methods. Two researchers searched seven databases for systematic reviews (SRs)/meta-analyses (MAs)...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2022/3967935 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832567073079820288 |
|---|---|
| author | Hongshuo Shi Dan Wang Wenqiang Chen Yinghao Li Guomin Si Tiantian Yang |
| author_facet | Hongshuo Shi Dan Wang Wenqiang Chen Yinghao Li Guomin Si Tiantian Yang |
| author_sort | Hongshuo Shi |
| collection | DOAJ |
| description | Objectives. Curcumin is a potential complementary treatment for ulcerative colitis (UC). This overview systematically summarizes and evaluates the existing evidence of curcumin in the treatment of UC. Methods. Two researchers searched seven databases for systematic reviews (SRs)/meta-analyses (MAs) which are about randomized controlled trials (RCTs) on curcumin for UC. Two researchers use the Assessment of Multiple Systematic Reviews 2 (AMSTAR-2), the Risk of Bias in Systematic Reviews (ROBIS) scale, the list of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to assess the included SRs/MAs. Results. Seven published SRs/MAs were included in our study. According to the results of the AMSTAR-2 assessment, all SRs/MAs are considered to be of very low quality. According to the ROBIS evaluation results, no SR/MA has been assessed as a low risk of bias. According to the results of the PRISMA checklist assessment, no SR/MA has been fully reported on the PRISMA checklist. According to GRADE, a total of 19 outcome indicators extracted from the included SRs/MAs were evaluated. The quality of evidence was 10 moderate, 6 low, and 3 very low. Conclusions. Curcumin may be an effective and safe complementary treatment for UC. However, further standard and comprehensive SRs/MAs and RCTs are needed to provide an evidence-based medical rationale for this. |
| format | Article |
| id | doaj-art-f8e874266b5e43cab0b79a6947b6b470 |
| institution | Kabale University |
| issn | 1687-630X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-f8e874266b5e43cab0b79a6947b6b4702025-02-03T01:02:29ZengWileyGastroenterology Research and Practice1687-630X2022-01-01202210.1155/2022/3967935Quality of Evidence Supporting the Role of Supplement Curcumin for the Treatment of Ulcerative Colitis: An Overview of Systematic ReviewsHongshuo Shi0Dan Wang1Wenqiang Chen2Yinghao Li3Guomin Si4Tiantian Yang5College of Traditional Chinese MedicineCollege of Traditional Chinese MedicineCollege of Traditional Chinese MedicineCollege of Traditional Chinese MedicineDepartment of Traditional Chinese MedicineDepartment of Traditional Chinese MedicineObjectives. Curcumin is a potential complementary treatment for ulcerative colitis (UC). This overview systematically summarizes and evaluates the existing evidence of curcumin in the treatment of UC. Methods. Two researchers searched seven databases for systematic reviews (SRs)/meta-analyses (MAs) which are about randomized controlled trials (RCTs) on curcumin for UC. Two researchers use the Assessment of Multiple Systematic Reviews 2 (AMSTAR-2), the Risk of Bias in Systematic Reviews (ROBIS) scale, the list of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to assess the included SRs/MAs. Results. Seven published SRs/MAs were included in our study. According to the results of the AMSTAR-2 assessment, all SRs/MAs are considered to be of very low quality. According to the ROBIS evaluation results, no SR/MA has been assessed as a low risk of bias. According to the results of the PRISMA checklist assessment, no SR/MA has been fully reported on the PRISMA checklist. According to GRADE, a total of 19 outcome indicators extracted from the included SRs/MAs were evaluated. The quality of evidence was 10 moderate, 6 low, and 3 very low. Conclusions. Curcumin may be an effective and safe complementary treatment for UC. However, further standard and comprehensive SRs/MAs and RCTs are needed to provide an evidence-based medical rationale for this.http://dx.doi.org/10.1155/2022/3967935 |
| spellingShingle | Hongshuo Shi Dan Wang Wenqiang Chen Yinghao Li Guomin Si Tiantian Yang Quality of Evidence Supporting the Role of Supplement Curcumin for the Treatment of Ulcerative Colitis: An Overview of Systematic Reviews Gastroenterology Research and Practice |
| title | Quality of Evidence Supporting the Role of Supplement Curcumin for the Treatment of Ulcerative Colitis: An Overview of Systematic Reviews |
| title_full | Quality of Evidence Supporting the Role of Supplement Curcumin for the Treatment of Ulcerative Colitis: An Overview of Systematic Reviews |
| title_fullStr | Quality of Evidence Supporting the Role of Supplement Curcumin for the Treatment of Ulcerative Colitis: An Overview of Systematic Reviews |
| title_full_unstemmed | Quality of Evidence Supporting the Role of Supplement Curcumin for the Treatment of Ulcerative Colitis: An Overview of Systematic Reviews |
| title_short | Quality of Evidence Supporting the Role of Supplement Curcumin for the Treatment of Ulcerative Colitis: An Overview of Systematic Reviews |
| title_sort | quality of evidence supporting the role of supplement curcumin for the treatment of ulcerative colitis an overview of systematic reviews |
| url | http://dx.doi.org/10.1155/2022/3967935 |
| work_keys_str_mv | AT hongshuoshi qualityofevidencesupportingtheroleofsupplementcurcuminforthetreatmentofulcerativecolitisanoverviewofsystematicreviews AT danwang qualityofevidencesupportingtheroleofsupplementcurcuminforthetreatmentofulcerativecolitisanoverviewofsystematicreviews AT wenqiangchen qualityofevidencesupportingtheroleofsupplementcurcuminforthetreatmentofulcerativecolitisanoverviewofsystematicreviews AT yinghaoli qualityofevidencesupportingtheroleofsupplementcurcuminforthetreatmentofulcerativecolitisanoverviewofsystematicreviews AT guominsi qualityofevidencesupportingtheroleofsupplementcurcuminforthetreatmentofulcerativecolitisanoverviewofsystematicreviews AT tiantianyang qualityofevidencesupportingtheroleofsupplementcurcuminforthetreatmentofulcerativecolitisanoverviewofsystematicreviews |