Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review

Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but...

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Bibliographic Details
Main Authors: Ayodele Atolagbe, Stanley Nkemjika, Olusegun Popoola, Oluwatoyin Oladeji, Irina Kogan, Haroon Saeed, Tolulope Olupona
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2021/3980872
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Summary:Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but rarely, blood dyscrasia adverse reactions have been reported. Hence, we report the case of a 56-year-old African American woman who developed severe neutropenia following two weeks of oral risperidone treatment. Her neutrophil levels returned to normal limits following discontinuation of risperidone and switching to haloperidol.
ISSN:2090-682X
2090-6838