Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm

Hypothyroidism is a common health issue worldwide with varying clinical manifestations. We report a woman who experienced an incomplete abortion and undiagnosed hypothyroidism who was referred to the oncologist with the suspicion of metastatic gestational trophoblastic neoplasm (GTN). A 29-year-old...

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Main Authors: Soheila Aminimoghaddam, Narmin Karisani, Maryam Mazloomi, Maryam Rahimi
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2016/3154267
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author Soheila Aminimoghaddam
Narmin Karisani
Maryam Mazloomi
Maryam Rahimi
author_facet Soheila Aminimoghaddam
Narmin Karisani
Maryam Mazloomi
Maryam Rahimi
author_sort Soheila Aminimoghaddam
collection DOAJ
description Hypothyroidism is a common health issue worldwide with varying clinical manifestations. We report a woman who experienced an incomplete abortion and undiagnosed hypothyroidism who was referred to the oncologist with the suspicion of metastatic gestational trophoblastic neoplasm (GTN). A 29-year-old woman with incomplete abortion was referred to an oncologist for possible GTN due to persistent active vaginal bleeding, an elevated beta human chorionic gonadotropin (hCG), abnormal cervical inspection exam, abnormal liver function tests, ovarian enlargement, ascites, and a pleural effusion. She was found to have hypothyroidism in further work-up. She was managed with thyroid hormone replacement therapy and her condition improved after 6 weeks. Complete resolution of the ovarian mass and pericardial and pleural effusion was achieved. This case describes an important experience; hypothyroidism should be considered in the differential diagnosis of any woman with an incomplete abortion presenting with an ovarian mass. Evaluation and correct diagnosis are important to prevent mismanagement.
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institution Kabale University
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spelling doaj-art-f8e5f28da73f49b4b91424311c85280a2025-02-03T05:50:58ZengWileyCase Reports in Oncological Medicine2090-67062090-67142016-01-01201610.1155/2016/31542673154267Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic NeoplasmSoheila Aminimoghaddam0Narmin Karisani1Maryam Mazloomi2Maryam Rahimi3Department of Obstetrics & Gynecology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, IranDepartment of Obstetrics & Gynecology, Shahid Akbar-Abadi Hospital, Iran University of Medical Sciences, Molavi Street, Tehran, IranDepartment of Obstetrics & Gynecology, School of Medicine, Shahid Akbar-Abadi Hospital, Iran University of Medical Sciences, Molavi Street, Tehran, IranDepartment of Obstetrics & Gynecology, School of Medicine, Shahid Akbar-Abadi Hospital, Iran University of Medical Sciences, Molavi Street, Tehran, IranHypothyroidism is a common health issue worldwide with varying clinical manifestations. We report a woman who experienced an incomplete abortion and undiagnosed hypothyroidism who was referred to the oncologist with the suspicion of metastatic gestational trophoblastic neoplasm (GTN). A 29-year-old woman with incomplete abortion was referred to an oncologist for possible GTN due to persistent active vaginal bleeding, an elevated beta human chorionic gonadotropin (hCG), abnormal cervical inspection exam, abnormal liver function tests, ovarian enlargement, ascites, and a pleural effusion. She was found to have hypothyroidism in further work-up. She was managed with thyroid hormone replacement therapy and her condition improved after 6 weeks. Complete resolution of the ovarian mass and pericardial and pleural effusion was achieved. This case describes an important experience; hypothyroidism should be considered in the differential diagnosis of any woman with an incomplete abortion presenting with an ovarian mass. Evaluation and correct diagnosis are important to prevent mismanagement.http://dx.doi.org/10.1155/2016/3154267
spellingShingle Soheila Aminimoghaddam
Narmin Karisani
Maryam Mazloomi
Maryam Rahimi
Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm
Case Reports in Oncological Medicine
title Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm
title_full Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm
title_fullStr Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm
title_full_unstemmed Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm
title_short Unusual Presentation of Hypothyroidism in a Pregnant Woman, Mimicking Gestational Trophoblastic Neoplasm
title_sort unusual presentation of hypothyroidism in a pregnant woman mimicking gestational trophoblastic neoplasm
url http://dx.doi.org/10.1155/2016/3154267
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AT narminkarisani unusualpresentationofhypothyroidisminapregnantwomanmimickinggestationaltrophoblasticneoplasm
AT maryammazloomi unusualpresentationofhypothyroidisminapregnantwomanmimickinggestationaltrophoblasticneoplasm
AT maryamrahimi unusualpresentationofhypothyroidisminapregnantwomanmimickinggestationaltrophoblasticneoplasm