Reaction of Acyl Chlorides with In Situ Formed Zinc Selenolates: Synthesis of Selenoesters versus Ring-Opening Reaction of Tetrahydrofuran

Attempting to apply the in situ production of PhSeZnSePh to the synthesis of selenoesters, an unexpected reaction involving the solvent (tetrahydrofuran) was observed and studied. We reported here some evidences about the mechanism and the possibility to control the chemoselectivity of this new reac...

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Main Authors: Gemma Bellino, Marialaura Scisciani, Jaqueline Pinto Vargas, Luca Sancineto, Luana Bagnoli, Francesca Marini, Diogo Seibert Lüdtke, Eder Joao Lenardao, Claudio Santi
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2016/2849140
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author Gemma Bellino
Marialaura Scisciani
Jaqueline Pinto Vargas
Luca Sancineto
Luana Bagnoli
Francesca Marini
Diogo Seibert Lüdtke
Eder Joao Lenardao
Claudio Santi
author_facet Gemma Bellino
Marialaura Scisciani
Jaqueline Pinto Vargas
Luca Sancineto
Luana Bagnoli
Francesca Marini
Diogo Seibert Lüdtke
Eder Joao Lenardao
Claudio Santi
author_sort Gemma Bellino
collection DOAJ
description Attempting to apply the in situ production of PhSeZnSePh to the synthesis of selenoesters, an unexpected reaction involving the solvent (tetrahydrofuran) was observed and studied. We reported here some evidences about the mechanism and the possibility to control the chemoselectivity of this new reaction that afforded the formation of interesting selenoderivatives in which the selenium moiety and the carboxylic one are spaced by four carbon units.
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institution DOAJ
issn 2090-9063
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language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Journal of Chemistry
spelling doaj-art-f8dde6489ef34739950e0ce4bf8a11f42025-08-20T03:20:05ZengWileyJournal of Chemistry2090-90632090-90712016-01-01201610.1155/2016/28491402849140Reaction of Acyl Chlorides with In Situ Formed Zinc Selenolates: Synthesis of Selenoesters versus Ring-Opening Reaction of TetrahydrofuranGemma Bellino0Marialaura Scisciani1Jaqueline Pinto Vargas2Luca Sancineto3Luana Bagnoli4Francesca Marini5Diogo Seibert Lüdtke6Eder Joao Lenardao7Claudio Santi8Group of Catalysis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia, ItalyGroup of Catalysis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia, ItalyInstituto de Química, Universidade Federal do Rio Grande do Sul (UFRGS), Avenida Bento Gonçalves 9500, 91501-970 Porto Alegre, RS, BrazilGroup of Catalysis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia, ItalyGroup of Catalysis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia, ItalyGroup of Catalysis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia, ItalyInstituto de Química, Universidade Federal do Rio Grande do Sul (UFRGS), Avenida Bento Gonçalves 9500, 91501-970 Porto Alegre, RS, BrazilLaboratório de Síntese Orgânica Limpa (LASOL), Centro de Ciências Químicas, Farmacêuticas e de Alimentos (CCQFA), Universidade Federal de Pelotas (UFPel), P.O. Box 354, 96010-900 Pelotas, RS, BrazilGroup of Catalysis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia, ItalyAttempting to apply the in situ production of PhSeZnSePh to the synthesis of selenoesters, an unexpected reaction involving the solvent (tetrahydrofuran) was observed and studied. We reported here some evidences about the mechanism and the possibility to control the chemoselectivity of this new reaction that afforded the formation of interesting selenoderivatives in which the selenium moiety and the carboxylic one are spaced by four carbon units.http://dx.doi.org/10.1155/2016/2849140
spellingShingle Gemma Bellino
Marialaura Scisciani
Jaqueline Pinto Vargas
Luca Sancineto
Luana Bagnoli
Francesca Marini
Diogo Seibert Lüdtke
Eder Joao Lenardao
Claudio Santi
Reaction of Acyl Chlorides with In Situ Formed Zinc Selenolates: Synthesis of Selenoesters versus Ring-Opening Reaction of Tetrahydrofuran
Journal of Chemistry
title Reaction of Acyl Chlorides with In Situ Formed Zinc Selenolates: Synthesis of Selenoesters versus Ring-Opening Reaction of Tetrahydrofuran
title_full Reaction of Acyl Chlorides with In Situ Formed Zinc Selenolates: Synthesis of Selenoesters versus Ring-Opening Reaction of Tetrahydrofuran
title_fullStr Reaction of Acyl Chlorides with In Situ Formed Zinc Selenolates: Synthesis of Selenoesters versus Ring-Opening Reaction of Tetrahydrofuran
title_full_unstemmed Reaction of Acyl Chlorides with In Situ Formed Zinc Selenolates: Synthesis of Selenoesters versus Ring-Opening Reaction of Tetrahydrofuran
title_short Reaction of Acyl Chlorides with In Situ Formed Zinc Selenolates: Synthesis of Selenoesters versus Ring-Opening Reaction of Tetrahydrofuran
title_sort reaction of acyl chlorides with in situ formed zinc selenolates synthesis of selenoesters versus ring opening reaction of tetrahydrofuran
url http://dx.doi.org/10.1155/2016/2849140
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