Overexpression of Delayed Rectifier K+ Channels Promotes In situ Proliferation of Leukocytes in Rat Kidneys with Advanced Chronic Renal Failure
Leukocytes, such as lymphocytes and macrophages, predominantly express delayed rectifier K+ channels (Kv1.3), and the channels play crucial roles in the activation and proliferation of the cells. Since lymphocytes are activated in patients with end-stage renal disease (ESRD), the channels expressed...
Saved in:
Main Authors: | Itsuro Kazama, Yoshio Maruyama, Yasuhiro Endo, Hiroaki Toyama, Yutaka Ejima, Mitsunobu Matsubara, Shin Kurosawa |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
|
Series: | International Journal of Nephrology |
Online Access: | http://dx.doi.org/10.1155/2012/581581 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Roles of Lymphocyte Kv1.3-Channels in the Pathogenesis of Renal Diseases and Novel Therapeutic Implications of Targeting the Channels
by: Itsuro Kazama
Published: (2015-01-01) -
Overexpression of DcR3 and Its Significance on Tumor Cell Differentiation and Proliferation in Glioma
by: Suning Huang, et al.
Published: (2014-01-01) -
A perturbation-based model for rectifier circuits
by: Vipin B. Vats, et al.
Published: (2006-01-01) -
Phenotyping of Leukocytes and Leukocyte-Derived Extracellular Vesicles
by: Lotte Hatting Pugholm, et al.
Published: (2016-01-01) -
In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell Carcinomas
by: Hjalmar G. Hagedorn, et al.
Published: (1998-01-01)