Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case Report
A 51-year-old man developed anorexia, dizziness, nausea, vomiting, and weight loss. He had orthostatic hypotension, hyponatremia, hyperkalemia, and hypocortisolemia, and the diagnosis of adrenal insufficiency was made. Magnetic resonance imaging (MRI) showed asymmetrically enlarged adrenal glands. B...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/574845 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832556237407911936 |
|---|---|
| author | Inan Anaforoglu Ekrem Algün Ömer Inceçayir Çigdem Siviloglu Ismail Caymaz |
| author_facet | Inan Anaforoglu Ekrem Algün Ömer Inceçayir Çigdem Siviloglu Ismail Caymaz |
| author_sort | Inan Anaforoglu |
| collection | DOAJ |
| description | A 51-year-old man developed anorexia, dizziness, nausea, vomiting, and weight loss. He had orthostatic hypotension, hyponatremia, hyperkalemia, and hypocortisolemia, and the diagnosis of adrenal insufficiency was made. Magnetic resonance imaging (MRI) showed asymmetrically enlarged adrenal glands. Biopsy of a hypoechoic, enlarged, inguinal lymph node showed caseating granulomas. Lumbar MRI showed vertebral body height loss and abnormal signal in L1 and L2; vertebral biopsy showed chronic, necrotic, caseating granulomatous inflammation consistent with tuberculous osteomyelitis. Clinical improvement occurred with isoniazid, rifampicin, pyrazinamide, and corticosteroids. The differential diagnosis of adrenal insufficiency should include tuberculosis, especially in geographic regions where tuberculosis is endemic. |
| format | Article |
| id | doaj-art-f89375558f4740ffb21a83519cea8b0e |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-f89375558f4740ffb21a83519cea8b0e2025-02-03T05:46:05ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/574845574845Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case ReportInan Anaforoglu0Ekrem Algün1Ömer Inceçayir2Çigdem Siviloglu3Ismail Caymaz4Department of Endocrinology and Metabolism, Trabzon Numune Education and Research Hospital, 61000 Trabzon, TurkeyDepartment of Endocrinology and Metabolism, Trabzon Numune Education and Research Hospital, 61000 Trabzon, TurkeyDepartment of Endocrinology and Metabolism, Trabzon Numune Education and Research Hospital, 61000 Trabzon, TurkeyDepartment of Pathology, Trabzon Numune Education and Research Hospital, 61000 Trabzon, TurkeyDepartment of Radiology, Trabzon Numune Education and Research Hospital, 61000 Trabzon, TurkeyA 51-year-old man developed anorexia, dizziness, nausea, vomiting, and weight loss. He had orthostatic hypotension, hyponatremia, hyperkalemia, and hypocortisolemia, and the diagnosis of adrenal insufficiency was made. Magnetic resonance imaging (MRI) showed asymmetrically enlarged adrenal glands. Biopsy of a hypoechoic, enlarged, inguinal lymph node showed caseating granulomas. Lumbar MRI showed vertebral body height loss and abnormal signal in L1 and L2; vertebral biopsy showed chronic, necrotic, caseating granulomatous inflammation consistent with tuberculous osteomyelitis. Clinical improvement occurred with isoniazid, rifampicin, pyrazinamide, and corticosteroids. The differential diagnosis of adrenal insufficiency should include tuberculosis, especially in geographic regions where tuberculosis is endemic.http://dx.doi.org/10.1155/2012/574845 |
| spellingShingle | Inan Anaforoglu Ekrem Algün Ömer Inceçayir Çigdem Siviloglu Ismail Caymaz Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case Report Case Reports in Medicine |
| title | Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case Report |
| title_full | Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case Report |
| title_fullStr | Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case Report |
| title_full_unstemmed | Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case Report |
| title_short | Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case Report |
| title_sort | acute adrenal insufficiency associated with tuberculous vertebral osteomyelitis and lymphadenopathy case report |
| url | http://dx.doi.org/10.1155/2012/574845 |
| work_keys_str_mv | AT inananaforoglu acuteadrenalinsufficiencyassociatedwithtuberculousvertebralosteomyelitisandlymphadenopathycasereport AT ekremalgun acuteadrenalinsufficiencyassociatedwithtuberculousvertebralosteomyelitisandlymphadenopathycasereport AT omerincecayir acuteadrenalinsufficiencyassociatedwithtuberculousvertebralosteomyelitisandlymphadenopathycasereport AT cigdemsiviloglu acuteadrenalinsufficiencyassociatedwithtuberculousvertebralosteomyelitisandlymphadenopathycasereport AT ismailcaymaz acuteadrenalinsufficiencyassociatedwithtuberculousvertebralosteomyelitisandlymphadenopathycasereport |