Mxene-bpV plays a neuroprotective role in cerebral ischemia-reperfusion injury by activating the Akt and promoting the M2 microglial polarization signaling pathways

Abstract Studies have shown that the inhibition of phosphatase and tensin homolog deleted on chromosome 10 (PTEN)was neuroprotective against ischemia/reperfusion(I/R) injury. Bisperoxovanadium (bpV), a derivative of vanadate, is a well-established inhibitor of PTEN. However, its function islimited d...

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Bibliographic Details
Main Authors: Jing Cheng, Han Yu, Zhi-Feng Zhang, Hong-Xiang Jiang, Ping Wu, Zhou-Guang Wang, Zhi-Biao Chen, Li-Quan Wu
Format: Article
Language:English
Published: Springer 2024-07-01
Series:Journal of Materials Science: Materials in Medicine
Subjects:
Online Access:https://doi.org/10.1007/s10856-024-06811-0
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