Autoantibody clusters in rheumatoid arthritis are not driven by antigen specificity or isotype

Autoantibody clusters in rheumatoid arthritis are not driven by antigen specificity or isotype

Objective Autoantibodies are a key feature of rheumatoid arthritis (RA). They can be detected years before disease onset, but it is unknown if there is any pattern in the co-occurrence of antigen recognition or isotype profiles. A common signature could point to a unique initial trigger for autoanti...

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Main Authors: Johan Rönnelid, Diane van der Woude, René E M Toes, Solbritt Rantapää-Dahlqvist, Heidi Kokkonen, Linda Johansson, Rachel Knevel, Tineke J van Wesemael, Marc P Maurits, Anouk G van Mourik
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/11/2/e005291.full
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