Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report

ABSTRACT Intrathecal methotrexate can cause cauda equina syndrome in pediatric ALL patients, as demonstrated in this rare case of an 8‐year‐old boy. Symptoms included progressive limb weakness and urinary retention. Early recognition, prompt discontinuation of the offending agent, and multidisciplin...

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Bibliographic Details
Main Authors: Marzieh Babaee, Mohsen Javadzadeh, Ali Hazeghi
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Clinical Case Reports
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Online Access:https://doi.org/10.1002/ccr3.70122
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Summary:ABSTRACT Intrathecal methotrexate can cause cauda equina syndrome in pediatric ALL patients, as demonstrated in this rare case of an 8‐year‐old boy. Symptoms included progressive limb weakness and urinary retention. Early recognition, prompt discontinuation of the offending agent, and multidisciplinary management are crucial. Vigilant neurological monitoring is essential for pediatric acute lymphoblastic leukemia patients receiving intrathecal chemotherapy.
ISSN:2050-0904