Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive Disorder

Drug therapy with selective serotonin reuptake inhibitors (SSRIs) has been used as a treatment for obsessive-compulsive disorder (OCD). In the present case report, exposure therapy was used in addition to escitalopram (20 mg) to treat a 28-year-old female patient with OCD for 6 months. Her obsessive...

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Main Authors: Mari Nakanishi, Harumi Oshita, Yoshihiro Tanaka, Ayako Inoue, Chiwa Kawashima, Kana Okamoto, Shunsuke Kobayashi, Yoshinobu Ishitobi, Taiga Ninomiya, Jotaro Akiyoshi
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2014/591023
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author Mari Nakanishi
Harumi Oshita
Yoshihiro Tanaka
Ayako Inoue
Chiwa Kawashima
Kana Okamoto
Shunsuke Kobayashi
Yoshinobu Ishitobi
Taiga Ninomiya
Jotaro Akiyoshi
author_facet Mari Nakanishi
Harumi Oshita
Yoshihiro Tanaka
Ayako Inoue
Chiwa Kawashima
Kana Okamoto
Shunsuke Kobayashi
Yoshinobu Ishitobi
Taiga Ninomiya
Jotaro Akiyoshi
author_sort Mari Nakanishi
collection DOAJ
description Drug therapy with selective serotonin reuptake inhibitors (SSRIs) has been used as a treatment for obsessive-compulsive disorder (OCD). In the present case report, exposure therapy was used in addition to escitalopram (20 mg) to treat a 28-year-old female patient with OCD for 6 months. Her obsessive-compulsive symptoms comprised thoughts of words such as rape, crematorium, neck hanging, unhappy, death, die, and kill and images such as a shelf of gods, a shrine, a Buddhist altar, the sun, the sky, and the faces of her parents, siblings, and relatives. As exposure therapy, she was asked to view the images associated with these symptoms three times a day along with drug therapy. With the combination of drug and exposure therapies, her obsessive-compulsive symptoms improved within 6 months, with no interference in her daily life. Multichannel near-infrared spectroscopy (NIRS) showed improvement of brain function in the temporal and frontal lobes after treatment. These results suggest that NIRS can be used as an indicator of brain function improvement in patients with OCD.
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institution Kabale University
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publishDate 2014-01-01
publisher Wiley
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spelling doaj-art-f8353b52a79744968d57048bd875ccb42025-02-03T07:23:32ZengWileyCase Reports in Psychiatry2090-682X2090-68382014-01-01201410.1155/2014/591023591023Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive DisorderMari Nakanishi0Harumi Oshita1Yoshihiro Tanaka2Ayako Inoue3Chiwa Kawashima4Kana Okamoto5Shunsuke Kobayashi6Yoshinobu Ishitobi7Taiga Ninomiya8Jotaro Akiyoshi9Department of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDepartment of Applied Linguistics, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDepartment of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDepartment of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDepartment of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDepartment of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDepartment of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDepartment of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDepartment of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDepartment of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-Machi, Oita 879-5593, JapanDrug therapy with selective serotonin reuptake inhibitors (SSRIs) has been used as a treatment for obsessive-compulsive disorder (OCD). In the present case report, exposure therapy was used in addition to escitalopram (20 mg) to treat a 28-year-old female patient with OCD for 6 months. Her obsessive-compulsive symptoms comprised thoughts of words such as rape, crematorium, neck hanging, unhappy, death, die, and kill and images such as a shelf of gods, a shrine, a Buddhist altar, the sun, the sky, and the faces of her parents, siblings, and relatives. As exposure therapy, she was asked to view the images associated with these symptoms three times a day along with drug therapy. With the combination of drug and exposure therapies, her obsessive-compulsive symptoms improved within 6 months, with no interference in her daily life. Multichannel near-infrared spectroscopy (NIRS) showed improvement of brain function in the temporal and frontal lobes after treatment. These results suggest that NIRS can be used as an indicator of brain function improvement in patients with OCD.http://dx.doi.org/10.1155/2014/591023
spellingShingle Mari Nakanishi
Harumi Oshita
Yoshihiro Tanaka
Ayako Inoue
Chiwa Kawashima
Kana Okamoto
Shunsuke Kobayashi
Yoshinobu Ishitobi
Taiga Ninomiya
Jotaro Akiyoshi
Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive Disorder
Case Reports in Psychiatry
title Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive Disorder
title_full Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive Disorder
title_fullStr Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive Disorder
title_full_unstemmed Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive Disorder
title_short Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive Disorder
title_sort near infrared spectroscopy during the verbal fluency task before and after treatment with image exposure and ssri therapy in patients with obsessive compulsive disorder
url http://dx.doi.org/10.1155/2014/591023
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