Isolation and Antibiotic Sensitivity Testing of Pseudomonas aeruginosa Isolates from Patients with Chronic Suppurative Otitis Media in Baghdad
Otitis media is one of the most common types of ear infections, plus bacteria are to blame. Pseudomonas aeruginosa is the most frequently diagnosed pathogen causing this infection. P. aeruginosa has virulence factors that lead to damage to the middle ear mucosa. This study was conducted to identif...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Baghdad
2025-01-01
|
| Series: | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| Subjects: | |
| Online Access: | https://jih.uobaghdad.edu.iq/index.php/j/article/view/3523 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832592041425502208 |
|---|---|
| author | Fatima Rheem Wadi Maryam Kareem Ali |
| author_facet | Fatima Rheem Wadi Maryam Kareem Ali |
| author_sort | Fatima Rheem Wadi |
| collection | DOAJ |
| description |
Otitis media is one of the most common types of ear infections, plus bacteria are to blame. Pseudomonas aeruginosa is the most frequently diagnosed pathogen causing this infection. P. aeruginosa has virulence factors that lead to damage to the middle ear mucosa. This study was conducted to identify Pseudomonas aeruginosa causing chronic suppurative otitis media and to determine its antibiotic sensitivity. A total of (100) ear swabs were collected from patients suffering from otitis media attending the ENT outpatient clinic at Baghdad Teaching Hospital from July 2022 till the end of December 2022. Age range was (18-75) years. Identification of bacteria and biochemical testing and antibiotic sensitivity test of the bacteria spp. were detection of 18 antibiotics for different types were carried out using the VITEK 2 automated system. The study showed the results as follows: Eighty positive cases, distributed among 32 (40%) males and 48 (60%) females. About 25% of patients are between 48-57 years old and 58-67 years old, respectively. A total of 55 patients (68.75%) were from urban areas, and 25 patients (31.25%) were from rural areas .With regard to the antibiotic susceptibility profile, the data showed that the most effective antibiotics were colistin(77%) Ceftazidime(55%) ,Cefepime(45%), Imipenem (42%), highest resistance percentages of strains to tested antibiotics was for Ceftoriaxone , Cefpodoxime (100%) and the lowest resistant percentages was (22.5%) for colistin Females were more likely to develop otitis media, and the prevalence appeared to be higher among the elderly. Pseudomonas aeruginosa represents the most implicated bacterial pathogen associated with this infection. colistin is the most effective antibiotic and can be considered as the drug of choice against P. aeruginosa.
|
| format | Article |
| id | doaj-art-f82b0614b04249a49762d7c9570ae7e6 |
| institution | Kabale University |
| issn | 1609-4042 2521-3407 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| spelling | doaj-art-f82b0614b04249a49762d7c9570ae7e62025-01-22T01:21:08ZengUniversity of BaghdadIbn Al-Haitham Journal for Pure and Applied Sciences1609-40422521-34072025-01-0138110.30526/38.1.3523Isolation and Antibiotic Sensitivity Testing of Pseudomonas aeruginosa Isolates from Patients with Chronic Suppurative Otitis Media in BaghdadFatima Rheem Wadi0https://orcid.org/0009-0007-7299-2474Maryam Kareem Ali1https://orcid.org/0000-0001-7853-9338Department of Microbiology, College of Medicine, University of Baghdad, Baghdad, IraqDepartment of Microbiology, College of Medicine, University of Baghdad, Baghdad, Iraq Otitis media is one of the most common types of ear infections, plus bacteria are to blame. Pseudomonas aeruginosa is the most frequently diagnosed pathogen causing this infection. P. aeruginosa has virulence factors that lead to damage to the middle ear mucosa. This study was conducted to identify Pseudomonas aeruginosa causing chronic suppurative otitis media and to determine its antibiotic sensitivity. A total of (100) ear swabs were collected from patients suffering from otitis media attending the ENT outpatient clinic at Baghdad Teaching Hospital from July 2022 till the end of December 2022. Age range was (18-75) years. Identification of bacteria and biochemical testing and antibiotic sensitivity test of the bacteria spp. were detection of 18 antibiotics for different types were carried out using the VITEK 2 automated system. The study showed the results as follows: Eighty positive cases, distributed among 32 (40%) males and 48 (60%) females. About 25% of patients are between 48-57 years old and 58-67 years old, respectively. A total of 55 patients (68.75%) were from urban areas, and 25 patients (31.25%) were from rural areas .With regard to the antibiotic susceptibility profile, the data showed that the most effective antibiotics were colistin(77%) Ceftazidime(55%) ,Cefepime(45%), Imipenem (42%), highest resistance percentages of strains to tested antibiotics was for Ceftoriaxone , Cefpodoxime (100%) and the lowest resistant percentages was (22.5%) for colistin Females were more likely to develop otitis media, and the prevalence appeared to be higher among the elderly. Pseudomonas aeruginosa represents the most implicated bacterial pathogen associated with this infection. colistin is the most effective antibiotic and can be considered as the drug of choice against P. aeruginosa. https://jih.uobaghdad.edu.iq/index.php/j/article/view/3523 Otitis media ear infection Pseudomonas aeruginosaantibiotic sensitivity of ear infection |
| spellingShingle | Fatima Rheem Wadi Maryam Kareem Ali Isolation and Antibiotic Sensitivity Testing of Pseudomonas aeruginosa Isolates from Patients with Chronic Suppurative Otitis Media in Baghdad Ibn Al-Haitham Journal for Pure and Applied Sciences Otitis media ear infection Pseudomonas aeruginosa antibiotic sensitivity of ear infection |
| title | Isolation and Antibiotic Sensitivity Testing of Pseudomonas aeruginosa Isolates from Patients with Chronic Suppurative Otitis Media in Baghdad |
| title_full | Isolation and Antibiotic Sensitivity Testing of Pseudomonas aeruginosa Isolates from Patients with Chronic Suppurative Otitis Media in Baghdad |
| title_fullStr | Isolation and Antibiotic Sensitivity Testing of Pseudomonas aeruginosa Isolates from Patients with Chronic Suppurative Otitis Media in Baghdad |
| title_full_unstemmed | Isolation and Antibiotic Sensitivity Testing of Pseudomonas aeruginosa Isolates from Patients with Chronic Suppurative Otitis Media in Baghdad |
| title_short | Isolation and Antibiotic Sensitivity Testing of Pseudomonas aeruginosa Isolates from Patients with Chronic Suppurative Otitis Media in Baghdad |
| title_sort | isolation and antibiotic sensitivity testing of pseudomonas aeruginosa isolates from patients with chronic suppurative otitis media in baghdad |
| topic | Otitis media ear infection Pseudomonas aeruginosa antibiotic sensitivity of ear infection |
| url | https://jih.uobaghdad.edu.iq/index.php/j/article/view/3523 |
| work_keys_str_mv | AT fatimarheemwadi isolationandantibioticsensitivitytestingofpseudomonasaeruginosaisolatesfrompatientswithchronicsuppurativeotitismediainbaghdad AT maryamkareemali isolationandantibioticsensitivitytestingofpseudomonasaeruginosaisolatesfrompatientswithchronicsuppurativeotitismediainbaghdad |