From gut to brain: Deciphering the impact of gut microbiota on neurological health
The Gut-Brain Axis is a complex and fascinating concept elucidating the two-way communication between gut microbiota and the central nervous system, encompassing diverse mechanisms with profound implications on neurological health. Situated in the gastrointestinal tract, the gut microbiota, a div...
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| Format: | Article |
| Language: | English |
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ResearchersLinks, Ltd
2024-03-01
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| Series: | Novel Research in Microbiology Journal |
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| Online Access: | https://nrmj.journals.ekb.eg/article_346872_e5b3e6c05134001a03006dd8dd93dbc8.pdf |
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| author | Gopinath R. Arundadhi M. Dhanasezhian A. Thangam G. Sucila |
| author_facet | Gopinath R. Arundadhi M. Dhanasezhian A. Thangam G. Sucila |
| author_sort | Gopinath R. |
| collection | DOAJ |
| description | The Gut-Brain Axis is a complex and fascinating concept elucidating the two-way
communication between gut microbiota and the central nervous system, encompassing diverse
mechanisms with profound implications on neurological health. Situated in the gastrointestinal
tract, the gut microbiota, a diverse bacterial community, which communicates with the brain
through various processes, including neurotransmitter and neuropeptide synthesis, immune
system modulation, and involvement of the vagus nerve. These interactions not only impact
digestion but also influence emotions, cognition, and behavior. Recent research has revealed
the significant influence of gut microbiota on the neurological health, establishing connections
between alterations in the gut microbiota composition and the prevailing conditions such as
depression and neurodegenerative diseases. This understanding sheds new light on the
pathophysiology of neurological disorders, marking the gut-brain axis as an exciting frontier in
neuroscience and medicine. The aims of this study were to investigate and elucidate the
intricate interplay between the gut microbiota and neurological health, and exploring the
mechanisms of communication along the gut-brain axis. As research progresses, the potential
for groundbreaking strategies to prevent and treat the neurological disorders becomes
increasingly apparent. This comprehensive review delves into the nuanced world of the gutbrain axis, providing insights into the intricate relationship between the gut and the brain.
Additionally, this review delves into potential therapeutic implications, exploring the use of
probiotics, prebiotics, and dietary interventions to modulate gut microbiota for enhancement of
the neurological well-being. |
| format | Article |
| id | doaj-art-f80d6de0c8ac43de9f45dba377bcdef8 |
| institution | OA Journals |
| issn | 2537-0286 2537-0294 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | ResearchersLinks, Ltd |
| record_format | Article |
| series | Novel Research in Microbiology Journal |
| spelling | doaj-art-f80d6de0c8ac43de9f45dba377bcdef82025-08-20T02:04:59ZengResearchersLinks, LtdNovel Research in Microbiology Journal2537-02862537-02942024-03-01822339235310.21608/NRMJ.2024.273319.1479From gut to brain: Deciphering the impact of gut microbiota on neurological healthGopinath R.0Arundadhi M.1Dhanasezhian A.2Thangam G. Sucila3Department of Microbiology, Government Theni Medical College, Theni, Tamil Nadu-625512, IndiaDepartment of Microbiology, Government Theni Medical College, Theni, Tamil Nadu-625512, IndiaDepartment of Microbiology, Government Theni Medical College, Theni, Tamil Nadu-625512, IndiaDepartment of Microbiology, Government Theni Medical College, Theni, Tamil Nadu-625512, IndiaThe Gut-Brain Axis is a complex and fascinating concept elucidating the two-way communication between gut microbiota and the central nervous system, encompassing diverse mechanisms with profound implications on neurological health. Situated in the gastrointestinal tract, the gut microbiota, a diverse bacterial community, which communicates with the brain through various processes, including neurotransmitter and neuropeptide synthesis, immune system modulation, and involvement of the vagus nerve. These interactions not only impact digestion but also influence emotions, cognition, and behavior. Recent research has revealed the significant influence of gut microbiota on the neurological health, establishing connections between alterations in the gut microbiota composition and the prevailing conditions such as depression and neurodegenerative diseases. This understanding sheds new light on the pathophysiology of neurological disorders, marking the gut-brain axis as an exciting frontier in neuroscience and medicine. The aims of this study were to investigate and elucidate the intricate interplay between the gut microbiota and neurological health, and exploring the mechanisms of communication along the gut-brain axis. As research progresses, the potential for groundbreaking strategies to prevent and treat the neurological disorders becomes increasingly apparent. This comprehensive review delves into the nuanced world of the gutbrain axis, providing insights into the intricate relationship between the gut and the brain. Additionally, this review delves into potential therapeutic implications, exploring the use of probiotics, prebiotics, and dietary interventions to modulate gut microbiota for enhancement of the neurological well-being.https://nrmj.journals.ekb.eg/article_346872_e5b3e6c05134001a03006dd8dd93dbc8.pdfgut-brain axisgut microbiotavagus nervedepressionneurological health |
| spellingShingle | Gopinath R. Arundadhi M. Dhanasezhian A. Thangam G. Sucila From gut to brain: Deciphering the impact of gut microbiota on neurological health Novel Research in Microbiology Journal gut-brain axis gut microbiota vagus nerve depression neurological health |
| title | From gut to brain: Deciphering the impact of gut microbiota on neurological health |
| title_full | From gut to brain: Deciphering the impact of gut microbiota on neurological health |
| title_fullStr | From gut to brain: Deciphering the impact of gut microbiota on neurological health |
| title_full_unstemmed | From gut to brain: Deciphering the impact of gut microbiota on neurological health |
| title_short | From gut to brain: Deciphering the impact of gut microbiota on neurological health |
| title_sort | from gut to brain deciphering the impact of gut microbiota on neurological health |
| topic | gut-brain axis gut microbiota vagus nerve depression neurological health |
| url | https://nrmj.journals.ekb.eg/article_346872_e5b3e6c05134001a03006dd8dd93dbc8.pdf |
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