Chemical profiling, antioxidant, and antimicrobial activities of the essential oil of Matricaria recutita (Chamomile)
Matricaria recutita, commonly known as chamomile, is extensively utilized in the pharmaceutical, cosmetic, and food industries for its medicinal and essential oil properties. Local people from the Karnali Province of Nepal use this plant against skin and vaginal infection by bacteria and fungi. Thi...
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Department of Physics, Mahendra Morang Adarsh Multiple Campus, Tribhuvan University
2025-01-01
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| Series: | Bibechana |
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| Online Access: | https://nepjol.info/index.php/BIBECHANA/article/view/66431 |
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| author | Ram Prasad Baral Rameshwar Adhikari Achyut Adhikari |
| author_facet | Ram Prasad Baral Rameshwar Adhikari Achyut Adhikari |
| author_sort | Ram Prasad Baral |
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Matricaria recutita, commonly known as chamomile, is extensively utilized in the pharmaceutical, cosmetic, and food industries for its medicinal and essential oil properties. Local people from the Karnali Province of Nepal use this plant against skin and vaginal infection by bacteria and fungi. This research focuses on extracting essential oil through hydro-distillation, followed by Gas Chromatography-Mass Spectroscopy (GC-MS) to identify its chemical constituents and antioxidant and antimicrobial activities against bacteria and fungi responsible for common skin infections. The GC-MS analysis of the essential oil from M. recutita identified eleven chemical components. The major constituents, with respective area percentages at retention times 37.16, 11.79, and 7.88 in the GC chromatogram, were -farnesene (46.56%), -bisabolol oxide-A (11.79%), and menthol (7.88%). Limonene, methyl salicylate, and -bisabolol oxide-B also constituted the lowest area percentages at 1.36%, 1.59%, and 1.62%, respectively. The essential oil exhibited significant antioxidant activity with IC50 = 0.1924 µL/mL. Additionally, the essential oil exhibited notable antibacterial activity against Staphylococcus aureus ATCC6538P and Candida albicans, displaying zones of inhibition measuring 10.64 mm and 14.44 mm, respectively. The broth method also revealed that the MIC is above the 250 mg/mL range and has more potential for inhibition.
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| format | Article |
| id | doaj-art-f800e2353e4049f098fa8f4f1a4467f7 |
| institution | Kabale University |
| issn | 2091-0762 2382-5340 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Department of Physics, Mahendra Morang Adarsh Multiple Campus, Tribhuvan University |
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| series | Bibechana |
| spelling | doaj-art-f800e2353e4049f098fa8f4f1a4467f72025-01-29T13:15:26ZengDepartment of Physics, Mahendra Morang Adarsh Multiple Campus, Tribhuvan UniversityBibechana2091-07622382-53402025-01-01221Chemical profiling, antioxidant, and antimicrobial activities of the essential oil of Matricaria recutita (Chamomile)Ram Prasad Baral0Rameshwar Adhikari1Achyut Adhikari2Central Department of Chemistry, Tribhuvan University, Kathmandu, NepalResearch Center Applied Science and Technology (RECAST), Kathmandu, NepalCentral Department of Chemistry, Tribhuvan University, Kathmandu, Nepal Matricaria recutita, commonly known as chamomile, is extensively utilized in the pharmaceutical, cosmetic, and food industries for its medicinal and essential oil properties. Local people from the Karnali Province of Nepal use this plant against skin and vaginal infection by bacteria and fungi. This research focuses on extracting essential oil through hydro-distillation, followed by Gas Chromatography-Mass Spectroscopy (GC-MS) to identify its chemical constituents and antioxidant and antimicrobial activities against bacteria and fungi responsible for common skin infections. The GC-MS analysis of the essential oil from M. recutita identified eleven chemical components. The major constituents, with respective area percentages at retention times 37.16, 11.79, and 7.88 in the GC chromatogram, were -farnesene (46.56%), -bisabolol oxide-A (11.79%), and menthol (7.88%). Limonene, methyl salicylate, and -bisabolol oxide-B also constituted the lowest area percentages at 1.36%, 1.59%, and 1.62%, respectively. The essential oil exhibited significant antioxidant activity with IC50 = 0.1924 µL/mL. Additionally, the essential oil exhibited notable antibacterial activity against Staphylococcus aureus ATCC6538P and Candida albicans, displaying zones of inhibition measuring 10.64 mm and 14.44 mm, respectively. The broth method also revealed that the MIC is above the 250 mg/mL range and has more potential for inhibition. https://nepjol.info/index.php/BIBECHANA/article/view/66431Matricaria recutita essential oil GC-MS analysis antibacterial antifungal antioxidant |
| spellingShingle | Ram Prasad Baral Rameshwar Adhikari Achyut Adhikari Chemical profiling, antioxidant, and antimicrobial activities of the essential oil of Matricaria recutita (Chamomile) Bibechana Matricaria recutita essential oil GC-MS analysis antibacterial antifungal antioxidant |
| title | Chemical profiling, antioxidant, and antimicrobial activities of the essential oil of Matricaria recutita (Chamomile) |
| title_full | Chemical profiling, antioxidant, and antimicrobial activities of the essential oil of Matricaria recutita (Chamomile) |
| title_fullStr | Chemical profiling, antioxidant, and antimicrobial activities of the essential oil of Matricaria recutita (Chamomile) |
| title_full_unstemmed | Chemical profiling, antioxidant, and antimicrobial activities of the essential oil of Matricaria recutita (Chamomile) |
| title_short | Chemical profiling, antioxidant, and antimicrobial activities of the essential oil of Matricaria recutita (Chamomile) |
| title_sort | chemical profiling antioxidant and antimicrobial activities of the essential oil of matricaria recutita chamomile |
| topic | Matricaria recutita essential oil GC-MS analysis antibacterial antifungal antioxidant |
| url | https://nepjol.info/index.php/BIBECHANA/article/view/66431 |
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