Subchondral Cellular Density Decreases with Increasing Grade of Cartilage Degeneration in Knee Osteoarthritis – An Ex vivo Histopathological Analysis

Subchondral Cellular Density Decreases with Increasing Grade of Cartilage Degeneration in Knee Osteoarthritis – An Ex vivo Histopathological Analysis

Introduction: Subchondral milieu has been the region of interest in recent clinical trials demonstrating it as an effective treatment focus in knee osteoarthritis (OA). However, a systematic analysis of the subchondral cell population density is lacking in knee OA. Hence, this study aims to analyze...

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Bibliographic Details
Main Authors: Sathish Muthu, Ragavi Kandasamy, Suryaprabha Palanisamy, Arun Anand Palaniappan
Format: Article
Language:English
Published: Indian Orthopaedic Research Group 2025-02-01
Series:Journal of Orthopaedic Case Reports
Subjects:
histopathology
knee osteoarthritis
subchondral zone
mesenchymal stromal cells
regenerative medicine
Online Access:https://jocr.co.in/wp/2025/02/01/subchondral-cellular-density-decreases-with-increasing-grade-of-cartilage-degeneration-in-knee-osteoarthritis-an-ex-vivo-histopathological-analysis/
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