Severe Symptomatic Hyponatremia Secondary to Escitalopram-Induced SIADH: A Case Report with Literature Review

Hyponatremia is a well-known medication related side effect of selective serotonin reuptake inhibitors; despite its association with escitalopram, the newest SSRI is very rare. We did a review of literature and came across only 14 reported case of this rare association of SIADH with escitalopram. We...

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Main Authors: Rishi Raj, Aasems Jacob, Ajay Venkatanarayan, Mohankumar Doraiswamy, Manjula Ashok
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2018/3697120
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author Rishi Raj
Aasems Jacob
Ajay Venkatanarayan
Mohankumar Doraiswamy
Manjula Ashok
author_facet Rishi Raj
Aasems Jacob
Ajay Venkatanarayan
Mohankumar Doraiswamy
Manjula Ashok
author_sort Rishi Raj
collection DOAJ
description Hyponatremia is a well-known medication related side effect of selective serotonin reuptake inhibitors; despite its association with escitalopram, the newest SSRI is very rare. We did a review of literature and came across only 14 reported case of this rare association of SIADH with escitalopram. We hereby report a case of a 93-year-old female who presented with generalized tonic-clonic seizure and was diagnosed with severe hyponatremia due to escitalopram-induced syndrome of inappropriate antidiuretic hormone secretion (SIADH). With this article, we want to emphasize clinicians about this rare side effect of escitalopram use and look for the risk factors leading to SIADH.
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institution Kabale University
issn 2090-6641
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language English
publishDate 2018-01-01
publisher Wiley
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series Case Reports in Nephrology
spelling doaj-art-f7f09a48e1124280931641f1bcd9917a2025-02-03T01:11:50ZengWileyCase Reports in Nephrology2090-66412090-665X2018-01-01201810.1155/2018/36971203697120Severe Symptomatic Hyponatremia Secondary to Escitalopram-Induced SIADH: A Case Report with Literature ReviewRishi Raj0Aasems Jacob1Ajay Venkatanarayan2Mohankumar Doraiswamy3Manjula Ashok4University of Kentucky, Lexington, KY 40536, USAUniversity of Kentucky, Lexington, KY 40536, USAMonmouth Medical Center, Long Branch, NJ 07740, USAMonmouth Medical Center, Long Branch, NJ 07740, USAMonmouth Medical Center, Long Branch, NJ 07740, USAHyponatremia is a well-known medication related side effect of selective serotonin reuptake inhibitors; despite its association with escitalopram, the newest SSRI is very rare. We did a review of literature and came across only 14 reported case of this rare association of SIADH with escitalopram. We hereby report a case of a 93-year-old female who presented with generalized tonic-clonic seizure and was diagnosed with severe hyponatremia due to escitalopram-induced syndrome of inappropriate antidiuretic hormone secretion (SIADH). With this article, we want to emphasize clinicians about this rare side effect of escitalopram use and look for the risk factors leading to SIADH.http://dx.doi.org/10.1155/2018/3697120
spellingShingle Rishi Raj
Aasems Jacob
Ajay Venkatanarayan
Mohankumar Doraiswamy
Manjula Ashok
Severe Symptomatic Hyponatremia Secondary to Escitalopram-Induced SIADH: A Case Report with Literature Review
Case Reports in Nephrology
title Severe Symptomatic Hyponatremia Secondary to Escitalopram-Induced SIADH: A Case Report with Literature Review
title_full Severe Symptomatic Hyponatremia Secondary to Escitalopram-Induced SIADH: A Case Report with Literature Review
title_fullStr Severe Symptomatic Hyponatremia Secondary to Escitalopram-Induced SIADH: A Case Report with Literature Review
title_full_unstemmed Severe Symptomatic Hyponatremia Secondary to Escitalopram-Induced SIADH: A Case Report with Literature Review
title_short Severe Symptomatic Hyponatremia Secondary to Escitalopram-Induced SIADH: A Case Report with Literature Review
title_sort severe symptomatic hyponatremia secondary to escitalopram induced siadh a case report with literature review
url http://dx.doi.org/10.1155/2018/3697120
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