Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 Interaction

Acute dystonic reactions are becoming much less prevalent in clinical practice due to the use of newer antipsychotics. Drug-drug interactions, patient characteristics, and environmental and genetic factors all contribute to the rate of occurrence of acute dystonia with second generation agents. In t...

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Main Authors: Sean Paul, Brian K. Cooke, Mathew Nguyen
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2013/136194
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author Sean Paul
Brian K. Cooke
Mathew Nguyen
author_facet Sean Paul
Brian K. Cooke
Mathew Nguyen
author_sort Sean Paul
collection DOAJ
description Acute dystonic reactions are becoming much less prevalent in clinical practice due to the use of newer antipsychotics. Drug-drug interactions, patient characteristics, and environmental and genetic factors all contribute to the rate of occurrence of acute dystonia with second generation agents. In this case, we report a glossopharyngeal dystonia secondary to a lurasidone-fluoxetine CYP-3A4 interaction to highlight the importance of maintaining an index of suspicion for laryngeal dystonia, a potentially fatal dystonia.
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institution Kabale University
issn 2090-682X
2090-6838
language English
publishDate 2013-01-01
publisher Wiley
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series Case Reports in Psychiatry
spelling doaj-art-f7d551752f8c4b51a756bff3b34de35d2025-02-03T06:00:46ZengWileyCase Reports in Psychiatry2090-682X2090-68382013-01-01201310.1155/2013/136194136194Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 InteractionSean Paul0Brian K. Cooke1Mathew Nguyen2University of Florida, Gainesville, FL 32606, USAUniversity of Florida, Gainesville, FL 32606, USAUniversity of Florida, Gainesville, FL 32606, USAAcute dystonic reactions are becoming much less prevalent in clinical practice due to the use of newer antipsychotics. Drug-drug interactions, patient characteristics, and environmental and genetic factors all contribute to the rate of occurrence of acute dystonia with second generation agents. In this case, we report a glossopharyngeal dystonia secondary to a lurasidone-fluoxetine CYP-3A4 interaction to highlight the importance of maintaining an index of suspicion for laryngeal dystonia, a potentially fatal dystonia.http://dx.doi.org/10.1155/2013/136194
spellingShingle Sean Paul
Brian K. Cooke
Mathew Nguyen
Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 Interaction
Case Reports in Psychiatry
title Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 Interaction
title_full Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 Interaction
title_fullStr Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 Interaction
title_full_unstemmed Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 Interaction
title_short Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 Interaction
title_sort glossopharyngeal dystonia secondary to a lurasidone fluoxetine cyp 3a4 interaction
url http://dx.doi.org/10.1155/2013/136194
work_keys_str_mv AT seanpaul glossopharyngealdystoniasecondarytoalurasidonefluoxetinecyp3a4interaction
AT briankcooke glossopharyngealdystoniasecondarytoalurasidonefluoxetinecyp3a4interaction
AT mathewnguyen glossopharyngealdystoniasecondarytoalurasidonefluoxetinecyp3a4interaction