The Gut Microbiome Profile in Obesity: A Systematic Review
Gut microbiome has been identified in the past decade as an important factor involved in obesity, but the magnitude of its contribution to obesity and its related comorbidities is still uncertain. Among the vast quantity of factors attributed to obesity, environmental, dietary, lifestyle, genetic, a...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2018/4095789 |
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| author | Olga Castaner Albert Goday Yong-Moon Park Seung-Hwan Lee Faidon Magkos Sue-Anne Toh Ee Shiow Helmut Schröder |
| author_facet | Olga Castaner Albert Goday Yong-Moon Park Seung-Hwan Lee Faidon Magkos Sue-Anne Toh Ee Shiow Helmut Schröder |
| author_sort | Olga Castaner |
| collection | DOAJ |
| description | Gut microbiome has been identified in the past decade as an important factor involved in obesity, but the magnitude of its contribution to obesity and its related comorbidities is still uncertain. Among the vast quantity of factors attributed to obesity, environmental, dietary, lifestyle, genetic, and others, the microbiome has aroused curiosity, and the scientific community has published many original articles. Most of the studies related to microbiome and obesity have been reported based on the associations between microbiota and obesity, and the in-depth study of the mechanisms related has been studied mainly in rodents and exceptionally in humans. Due to the quantity and diverse information published, the need of reviews is mandatory to recapitulate the relevant achievements. In this systematic review, we provide an overview of the current evidence on the association between intestinal microbiota and obesity. Additionally, we analyze the effects of an extreme weight loss intervention such as bariatric surgery on gut microbiota. The review is divided into 2 sections: first, the association of obesity and related metabolic disorders with different gut microbiome profiles, including metagenomics studies, and second, changes on gut microbiome after an extreme weight loss intervention such as bariatric surgery. |
| format | Article |
| id | doaj-art-f7ca809d72f141449104cd2b99d86c85 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-f7ca809d72f141449104cd2b99d86c852025-02-03T01:20:53ZengWileyInternational Journal of Endocrinology1687-83371687-83452018-01-01201810.1155/2018/40957894095789The Gut Microbiome Profile in Obesity: A Systematic ReviewOlga Castaner0Albert Goday1Yong-Moon Park2Seung-Hwan Lee3Faidon Magkos4Sue-Anne Toh Ee Shiow5Helmut Schröder6Cardiovascular Risk and Nutrition Research Group, Hospital del Mar Research Institute (IMIM), Barcelona, SpainCIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Santiago de Compostela, SpainEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USADivision of Endocrinology & Metabolism, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS) and Clinical Nutrition Research Centre (CNRC), Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), SingaporeYong Loo Lin School of Medicine, National University of Singapore, SingaporeCardiovascular Risk and Nutrition Research Group, Hospital del Mar Research Institute (IMIM), Barcelona, SpainGut microbiome has been identified in the past decade as an important factor involved in obesity, but the magnitude of its contribution to obesity and its related comorbidities is still uncertain. Among the vast quantity of factors attributed to obesity, environmental, dietary, lifestyle, genetic, and others, the microbiome has aroused curiosity, and the scientific community has published many original articles. Most of the studies related to microbiome and obesity have been reported based on the associations between microbiota and obesity, and the in-depth study of the mechanisms related has been studied mainly in rodents and exceptionally in humans. Due to the quantity and diverse information published, the need of reviews is mandatory to recapitulate the relevant achievements. In this systematic review, we provide an overview of the current evidence on the association between intestinal microbiota and obesity. Additionally, we analyze the effects of an extreme weight loss intervention such as bariatric surgery on gut microbiota. The review is divided into 2 sections: first, the association of obesity and related metabolic disorders with different gut microbiome profiles, including metagenomics studies, and second, changes on gut microbiome after an extreme weight loss intervention such as bariatric surgery.http://dx.doi.org/10.1155/2018/4095789 |
| spellingShingle | Olga Castaner Albert Goday Yong-Moon Park Seung-Hwan Lee Faidon Magkos Sue-Anne Toh Ee Shiow Helmut Schröder The Gut Microbiome Profile in Obesity: A Systematic Review International Journal of Endocrinology |
| title | The Gut Microbiome Profile in Obesity: A Systematic Review |
| title_full | The Gut Microbiome Profile in Obesity: A Systematic Review |
| title_fullStr | The Gut Microbiome Profile in Obesity: A Systematic Review |
| title_full_unstemmed | The Gut Microbiome Profile in Obesity: A Systematic Review |
| title_short | The Gut Microbiome Profile in Obesity: A Systematic Review |
| title_sort | gut microbiome profile in obesity a systematic review |
| url | http://dx.doi.org/10.1155/2018/4095789 |
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