Unlocking mRNA Vaccine Potential in Liver Cancer Treatment via Synergistic Bile Acid Modulation

Unlocking mRNA Vaccine Potential in Liver Cancer Treatment via Synergistic Bile Acid Modulation

This Letter to the Editor explores synergistic mechanisms enhancing mRNA cancer vaccine efficacy through bile acid metabolism modulation in liver cancer treatment. The latest evidence indicates that bile acids significantly impair T cell function within the liver cancer microenvironment, creating an...

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Bibliographic Details
Main Authors: Yuqian Wang, Rui Han, Changquan Ling
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Vaccines
Subjects:
bile acid
mRNA cancer vaccine
liver cancer
combinatorial therapeutic approach
Online Access:https://www.mdpi.com/2076-393X/13/5/502
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