IL-6/IL-6R Signaling Blockade Alleviates Chronic Allograft Rejection by Modulating Germinal Center B Cells and Allograft Inflammation in Murine Cardiac Transplantation

IL-6/IL-6R Signaling Blockade Alleviates Chronic Allograft Rejection by Modulating Germinal Center B Cells and Allograft Inflammation in Murine Cardiac Transplantation

Renfei Xia,1,* Xiaoyi Shi,2,* Hengcheng Zhang,3,* Wenli Zeng,1 Zhe Yang,4 Jian Xu,1 Jianning Wang,4 Yun Miao,1 Tao Liao1,4 1Department of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People’s Republic of China; 2Department of...

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Bibliographic Details
Main Authors: Xia R, Shi X, Zhang H, Zeng W, Yang Z, Xu J, Wang J, Miao Y, Liao T
Format: Article
Language:English
Published: Dove Medical Press 2025-07-01
Series:Journal of Inflammation Research
Subjects:
IL-6
IL-6R
chronic rejection
tocilizumab
cardiac transplantation
Online Access:https://www.dovepress.com/il-6il-6r-signaling-blockade-alleviates-chronic-allograft-rejection-by-peer-reviewed-fulltext-article-JIR
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