Synthesis of N-Methyl-6-heterocyclic-1-oxoisoindoline Derivatives by Microwave Assisted Buchwald-Hartwig Amination

An rapid and efficient microwave assisted Pd(II) catalyzed protocol for the preparation of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by Buchwald-Hartwig amination with an overall yield 68-85% has been described.

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Main Authors: C. Kishor Kumar, H. Vijay Kumar, Nagaraja Naik
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2011/851935
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author C. Kishor Kumar
H. Vijay Kumar
Nagaraja Naik
author_facet C. Kishor Kumar
H. Vijay Kumar
Nagaraja Naik
author_sort C. Kishor Kumar
collection DOAJ
description An rapid and efficient microwave assisted Pd(II) catalyzed protocol for the preparation of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by Buchwald-Hartwig amination with an overall yield 68-85% has been described.
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institution Kabale University
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publisher Wiley
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spelling doaj-art-f7a29c509cc64df185a6ba223c8769462025-02-03T01:28:36ZengWileyE-Journal of Chemistry0973-49452090-98102011-01-01831108111310.1155/2011/851935Synthesis of N-Methyl-6-heterocyclic-1-oxoisoindoline Derivatives by Microwave Assisted Buchwald-Hartwig AminationC. Kishor Kumar0H. Vijay Kumar1Nagaraja Naik2Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570 006, Karnataka, IndiaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570 006, Karnataka, IndiaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570 006, Karnataka, IndiaAn rapid and efficient microwave assisted Pd(II) catalyzed protocol for the preparation of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by Buchwald-Hartwig amination with an overall yield 68-85% has been described.http://dx.doi.org/10.1155/2011/851935
spellingShingle C. Kishor Kumar
H. Vijay Kumar
Nagaraja Naik
Synthesis of N-Methyl-6-heterocyclic-1-oxoisoindoline Derivatives by Microwave Assisted Buchwald-Hartwig Amination
E-Journal of Chemistry
title Synthesis of N-Methyl-6-heterocyclic-1-oxoisoindoline Derivatives by Microwave Assisted Buchwald-Hartwig Amination
title_full Synthesis of N-Methyl-6-heterocyclic-1-oxoisoindoline Derivatives by Microwave Assisted Buchwald-Hartwig Amination
title_fullStr Synthesis of N-Methyl-6-heterocyclic-1-oxoisoindoline Derivatives by Microwave Assisted Buchwald-Hartwig Amination
title_full_unstemmed Synthesis of N-Methyl-6-heterocyclic-1-oxoisoindoline Derivatives by Microwave Assisted Buchwald-Hartwig Amination
title_short Synthesis of N-Methyl-6-heterocyclic-1-oxoisoindoline Derivatives by Microwave Assisted Buchwald-Hartwig Amination
title_sort synthesis of n methyl 6 heterocyclic 1 oxoisoindoline derivatives by microwave assisted buchwald hartwig amination
url http://dx.doi.org/10.1155/2011/851935
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AT hvijaykumar synthesisofnmethyl6heterocyclic1oxoisoindolinederivativesbymicrowaveassistedbuchwaldhartwigamination
AT nagarajanaik synthesisofnmethyl6heterocyclic1oxoisoindolinederivativesbymicrowaveassistedbuchwaldhartwigamination