Induction of Oxidative Stress in Kidney

Oxidative stress has a critical role in the pathophysiology of several kidney diseases, and many complications of these diseases are mediated by oxidative stress, oxidative stress-related mediators, and inflammation. Several systemic diseases such as hypertension, diabetes mellitus, and hypercholest...

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Main Author: Emin Ozbek
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Nephrology
Online Access:http://dx.doi.org/10.1155/2012/465897
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author Emin Ozbek
author_facet Emin Ozbek
author_sort Emin Ozbek
collection DOAJ
description Oxidative stress has a critical role in the pathophysiology of several kidney diseases, and many complications of these diseases are mediated by oxidative stress, oxidative stress-related mediators, and inflammation. Several systemic diseases such as hypertension, diabetes mellitus, and hypercholesterolemia; infection; antibiotics, chemotherapeutics, and radiocontrast agents; and environmental toxins, occupational chemicals, radiation, smoking, as well as alcohol consumption induce oxidative stress in kidney. We searched the literature using PubMed, MEDLINE, and Google scholar with “oxidative stress, reactive oxygen species, oxygen free radicals, kidney, renal injury, nephropathy, nephrotoxicity, and induction”. The literature search included only articles written in English language. Letters or case reports were excluded. Scientific relevance, for clinical studies target populations, and study design, for basic science studies full coverage of main topics, are eligibility criteria for articles used in this paper.
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institution Kabale University
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series International Journal of Nephrology
spelling doaj-art-f78b89792d7a4e738b5db830b0d08bc12025-02-03T05:43:54ZengWileyInternational Journal of Nephrology2090-214X2090-21582012-01-01201210.1155/2012/465897465897Induction of Oxidative Stress in KidneyEmin Ozbek0Department of Urology, Okmeydani Research & Education Hospital, Sisli, 34384 Istanbul, TurkeyOxidative stress has a critical role in the pathophysiology of several kidney diseases, and many complications of these diseases are mediated by oxidative stress, oxidative stress-related mediators, and inflammation. Several systemic diseases such as hypertension, diabetes mellitus, and hypercholesterolemia; infection; antibiotics, chemotherapeutics, and radiocontrast agents; and environmental toxins, occupational chemicals, radiation, smoking, as well as alcohol consumption induce oxidative stress in kidney. We searched the literature using PubMed, MEDLINE, and Google scholar with “oxidative stress, reactive oxygen species, oxygen free radicals, kidney, renal injury, nephropathy, nephrotoxicity, and induction”. The literature search included only articles written in English language. Letters or case reports were excluded. Scientific relevance, for clinical studies target populations, and study design, for basic science studies full coverage of main topics, are eligibility criteria for articles used in this paper.http://dx.doi.org/10.1155/2012/465897
spellingShingle Emin Ozbek
Induction of Oxidative Stress in Kidney
International Journal of Nephrology
title Induction of Oxidative Stress in Kidney
title_full Induction of Oxidative Stress in Kidney
title_fullStr Induction of Oxidative Stress in Kidney
title_full_unstemmed Induction of Oxidative Stress in Kidney
title_short Induction of Oxidative Stress in Kidney
title_sort induction of oxidative stress in kidney
url http://dx.doi.org/10.1155/2012/465897
work_keys_str_mv AT eminozbek inductionofoxidativestressinkidney