Application of Laparoscopic Radical Resection for Type III and IV Hilar Cholangiocarcinoma Treatment
Background. This study is aimed at investigating the feasibility and safety of the laparoscopic radical resection for treating type III and IV hilar cholangiocarcinoma (III/IV Hilar C). Methods. Six patients with III/IV Hilar C were enrolled in our hospital. All patients underwent total laparoscopic...
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Wiley
2020-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/1506275 |
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| author | Sulai Liu Xinyu Liu Xuepeng Li Ou Li Weimin Yi Junaid Khan Pingzhou Yang Chao Guo Chuang Peng Bo Jiang |
| author_facet | Sulai Liu Xinyu Liu Xuepeng Li Ou Li Weimin Yi Junaid Khan Pingzhou Yang Chao Guo Chuang Peng Bo Jiang |
| author_sort | Sulai Liu |
| collection | DOAJ |
| description | Background. This study is aimed at investigating the feasibility and safety of the laparoscopic radical resection for treating type III and IV hilar cholangiocarcinoma (III/IV Hilar C). Methods. Six patients with III/IV Hilar C were enrolled in our hospital. All patients underwent total laparoscopic surgery, including basic surgery (laparoscopic gallbladder, hilar bile duct, and common bile duct resection and hepatoduodenal ligament lymph node dissection) combined with left hepatic and caudate lobe resection/portal resection. The tumor size, operation time, intraoperative blood loss, and postoperative complications were observed. The follow-up of the patients after discharge was recorded. Results. Surgery was successfully completed in 6 patients. We found that the tumor size of 6 patients ranged from 1.5 to 3.6 cm, with 4 lymph nodes. The operation time was 540-660 minutes, and the blood loss was 300-500 ml. One patient developed bile leakage after surgery, healed within 2 weeks after drainage. The postoperative hospital stay was 16 (13-24) days. There were 4 cases of negative bile duct margin tumor, 1 case was positive, and 1 case was not reported. All 6 patients were discharged smoothly without perioperative death. Regular examinations were conducted every 3 months after discharge, and the median duration was 7 months. Only 1 patient had a marginal dysplasia, and 5 patients had no obvious signs of recurrence. Conclusions. Application of laparoscopic radical resection for III/IV Hilar C is safe and feasible and has good short-term efficacy with adequate preoperative evaluation, appropriate case selection, and precise operative strategy. |
| format | Article |
| id | doaj-art-f7863177550c46918d43e491fee3eb7a |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-f7863177550c46918d43e491fee3eb7a2025-02-03T06:04:38ZengWileyGastroenterology Research and Practice1687-61211687-630X2020-01-01202010.1155/2020/15062751506275Application of Laparoscopic Radical Resection for Type III and IV Hilar Cholangiocarcinoma TreatmentSulai Liu0Xinyu Liu1Xuepeng Li2Ou Li3Weimin Yi4Junaid Khan5Pingzhou Yang6Chao Guo7Chuang Peng8Bo Jiang9Department of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaDepartment of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaDepartment of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaDepartment of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaDepartment of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaDepartment of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaDepartment of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaDepartment of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaDepartment of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaDepartment of Hepatobiliary Surgery, Hunan Provincial People’s Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, 410005 Hunan Province, ChinaBackground. This study is aimed at investigating the feasibility and safety of the laparoscopic radical resection for treating type III and IV hilar cholangiocarcinoma (III/IV Hilar C). Methods. Six patients with III/IV Hilar C were enrolled in our hospital. All patients underwent total laparoscopic surgery, including basic surgery (laparoscopic gallbladder, hilar bile duct, and common bile duct resection and hepatoduodenal ligament lymph node dissection) combined with left hepatic and caudate lobe resection/portal resection. The tumor size, operation time, intraoperative blood loss, and postoperative complications were observed. The follow-up of the patients after discharge was recorded. Results. Surgery was successfully completed in 6 patients. We found that the tumor size of 6 patients ranged from 1.5 to 3.6 cm, with 4 lymph nodes. The operation time was 540-660 minutes, and the blood loss was 300-500 ml. One patient developed bile leakage after surgery, healed within 2 weeks after drainage. The postoperative hospital stay was 16 (13-24) days. There were 4 cases of negative bile duct margin tumor, 1 case was positive, and 1 case was not reported. All 6 patients were discharged smoothly without perioperative death. Regular examinations were conducted every 3 months after discharge, and the median duration was 7 months. Only 1 patient had a marginal dysplasia, and 5 patients had no obvious signs of recurrence. Conclusions. Application of laparoscopic radical resection for III/IV Hilar C is safe and feasible and has good short-term efficacy with adequate preoperative evaluation, appropriate case selection, and precise operative strategy.http://dx.doi.org/10.1155/2020/1506275 |
| spellingShingle | Sulai Liu Xinyu Liu Xuepeng Li Ou Li Weimin Yi Junaid Khan Pingzhou Yang Chao Guo Chuang Peng Bo Jiang Application of Laparoscopic Radical Resection for Type III and IV Hilar Cholangiocarcinoma Treatment Gastroenterology Research and Practice |
| title | Application of Laparoscopic Radical Resection for Type III and IV Hilar Cholangiocarcinoma Treatment |
| title_full | Application of Laparoscopic Radical Resection for Type III and IV Hilar Cholangiocarcinoma Treatment |
| title_fullStr | Application of Laparoscopic Radical Resection for Type III and IV Hilar Cholangiocarcinoma Treatment |
| title_full_unstemmed | Application of Laparoscopic Radical Resection for Type III and IV Hilar Cholangiocarcinoma Treatment |
| title_short | Application of Laparoscopic Radical Resection for Type III and IV Hilar Cholangiocarcinoma Treatment |
| title_sort | application of laparoscopic radical resection for type iii and iv hilar cholangiocarcinoma treatment |
| url | http://dx.doi.org/10.1155/2020/1506275 |
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