Evolution of the Apicomplexan Sugar Transporter Gene Family Repertoire

Apicomplexan protist parasites utilize host sugars transported into the parasite by sugar transporter proteins for use as an energy source. We performed a phylum-wide phylogenetic analysis of the apicomplexan sugar transporter repertoire. Phylogenetic analyses revealed six major subfamilies of apico...

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Bibliographic Details
Main Authors: Ousman Mahmud, Jessica C. Kissinger
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2017/1707231
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Summary:Apicomplexan protist parasites utilize host sugars transported into the parasite by sugar transporter proteins for use as an energy source. We performed a phylum-wide phylogenetic analysis of the apicomplexan sugar transporter repertoire. Phylogenetic analyses revealed six major subfamilies of apicomplexan sugar transporters. Transporters in one subfamily have undergone expansions in Piroplasma species and Gregarina niphandrodes, while other subfamilies are highly divergent and contain genes found in only one or two species. Analyses of the divergent apicomplexan subfamilies revealed their presence in ciliates, indicating their alveolate ancestry and subsequent loss in chromerids and many apicomplexans.
ISSN:2314-436X
2314-4378