Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration
Erectile dysfunction (ED) is an important cause of reduced quality of life for men and their partners. Recent studies have found that cavernous nerve injury (CNI) during prostate cancer surgery and other pelvic surgery results in medically induced CNIED in more than 80% of patients. The efficacy of...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2021/5353785 |
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| author | Nan Jiang Cheng Wu Xunrong Zhou Guanghua Zhai Jian Wu |
| author_facet | Nan Jiang Cheng Wu Xunrong Zhou Guanghua Zhai Jian Wu |
| author_sort | Nan Jiang |
| collection | DOAJ |
| description | Erectile dysfunction (ED) is an important cause of reduced quality of life for men and their partners. Recent studies have found that cavernous nerve injury (CNI) during prostate cancer surgery and other pelvic surgery results in medically induced CNIED in more than 80% of patients. The efficacy of first- and second-line treatment options for ED is poor. A great deal of research has been devoted to exploring new methods of neuroprotection and nerve regeneration to save erectile function in patients with CNIED, especially in patients with cavernous nerve injury after prostate cancer surgery. In addition, such as neuromodulatory proteins, proimmune ligands, gene therapy, stem cell therapy, and the current cutting-edge low-energy shock wave therapy have shown advantages in basic research and limited clinical studies. In the context of today’s modern medicine, these new therapeutic techniques are expected to be new tools in the treatment of cavernous nerve injury erectile dysfunction. This article presents the main causes, mechanisms, and treatment of cavernous nerve injury erectile dysfunction and combines them with new treatment strategies. |
| format | Article |
| id | doaj-art-f74267fa5fd74a918e6f4b1b8e3c6b5f |
| institution | Kabale University |
| issn | 2314-7156 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-f74267fa5fd74a918e6f4b1b8e3c6b5f2025-02-03T05:47:00ZengWileyJournal of Immunology Research2314-71562021-01-01202110.1155/2021/5353785Cavernous Nerve Injury Resulted Erectile Dysfunction and RegenerationNan Jiang0Cheng Wu1Xunrong Zhou2Guanghua Zhai3Jian Wu4Department of UrologyDepartment of UrologyDepartment of UrologyDepartment of Clinical LaboratoryDepartment of Clinical LaboratoryErectile dysfunction (ED) is an important cause of reduced quality of life for men and their partners. Recent studies have found that cavernous nerve injury (CNI) during prostate cancer surgery and other pelvic surgery results in medically induced CNIED in more than 80% of patients. The efficacy of first- and second-line treatment options for ED is poor. A great deal of research has been devoted to exploring new methods of neuroprotection and nerve regeneration to save erectile function in patients with CNIED, especially in patients with cavernous nerve injury after prostate cancer surgery. In addition, such as neuromodulatory proteins, proimmune ligands, gene therapy, stem cell therapy, and the current cutting-edge low-energy shock wave therapy have shown advantages in basic research and limited clinical studies. In the context of today’s modern medicine, these new therapeutic techniques are expected to be new tools in the treatment of cavernous nerve injury erectile dysfunction. This article presents the main causes, mechanisms, and treatment of cavernous nerve injury erectile dysfunction and combines them with new treatment strategies.http://dx.doi.org/10.1155/2021/5353785 |
| spellingShingle | Nan Jiang Cheng Wu Xunrong Zhou Guanghua Zhai Jian Wu Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration Journal of Immunology Research |
| title | Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration |
| title_full | Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration |
| title_fullStr | Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration |
| title_full_unstemmed | Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration |
| title_short | Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration |
| title_sort | cavernous nerve injury resulted erectile dysfunction and regeneration |
| url | http://dx.doi.org/10.1155/2021/5353785 |
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