Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far
The nervous system is essential for normal physiological function of all systems within the human body. Unfortunately the nervous system has a limited capacity for self-repair and there are a plethora of disorders, diseases, and types of trauma that affect the central and peripheral nervous systems;...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Photoenergy |
| Online Access: | http://dx.doi.org/10.1155/2014/827540 |
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| author | T. J. Moore Heidi Abrahamse |
| author_facet | T. J. Moore Heidi Abrahamse |
| author_sort | T. J. Moore |
| collection | DOAJ |
| description | The nervous system is essential for normal physiological function of all systems within the human body. Unfortunately the nervous system has a limited capacity for self-repair and there are a plethora of disorders, diseases, and types of trauma that affect the central and peripheral nervous systems; however, current treatment modalities are unable to remedy them. Stem cell therapy using easily accessible mesenchymal stem cells, such as those found in the adipose stroma, has come to the fore in a number of biomedical disciplines as a potential therapeutic regime. In addition to substantial research already having been conducted on the in vitro differentiation of stem cells for the treatment of neurological repair, numerous strategies for the induction and culture of stem cells into terminal neural lineages have also been developed. However, none of these strategies have yet been able to produce a fully functional descendent suitable for use in stem cell therapy. Due to the positive effects that low level laser irradiation has shown in stem cell studies to date, we propose that it could enhance the processes involved in the differentiation of adipose derived stem cells into neuronal lineages. |
| format | Article |
| id | doaj-art-f73a1addc277487083e446e3f330370d |
| institution | Kabale University |
| issn | 1110-662X 1687-529X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Photoenergy |
| spelling | doaj-art-f73a1addc277487083e446e3f330370d2025-02-03T06:00:45ZengWileyInternational Journal of Photoenergy1110-662X1687-529X2014-01-01201410.1155/2014/827540827540Neuronal Differentiation of Adipose Derived Stem Cells: Progress So FarT. J. Moore0Heidi Abrahamse1Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein 2028, South AfricaLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein 2028, South AfricaThe nervous system is essential for normal physiological function of all systems within the human body. Unfortunately the nervous system has a limited capacity for self-repair and there are a plethora of disorders, diseases, and types of trauma that affect the central and peripheral nervous systems; however, current treatment modalities are unable to remedy them. Stem cell therapy using easily accessible mesenchymal stem cells, such as those found in the adipose stroma, has come to the fore in a number of biomedical disciplines as a potential therapeutic regime. In addition to substantial research already having been conducted on the in vitro differentiation of stem cells for the treatment of neurological repair, numerous strategies for the induction and culture of stem cells into terminal neural lineages have also been developed. However, none of these strategies have yet been able to produce a fully functional descendent suitable for use in stem cell therapy. Due to the positive effects that low level laser irradiation has shown in stem cell studies to date, we propose that it could enhance the processes involved in the differentiation of adipose derived stem cells into neuronal lineages.http://dx.doi.org/10.1155/2014/827540 |
| spellingShingle | T. J. Moore Heidi Abrahamse Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far International Journal of Photoenergy |
| title | Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far |
| title_full | Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far |
| title_fullStr | Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far |
| title_full_unstemmed | Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far |
| title_short | Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far |
| title_sort | neuronal differentiation of adipose derived stem cells progress so far |
| url | http://dx.doi.org/10.1155/2014/827540 |
| work_keys_str_mv | AT tjmoore neuronaldifferentiationofadiposederivedstemcellsprogresssofar AT heidiabrahamse neuronaldifferentiationofadiposederivedstemcellsprogresssofar |