Brucella infection in a dairy herd of Chattogram, Bangladesh

Objective: This study aimed to confirm probable causes of abortion with subsequent characterization of Brucella isolates from a dairy herd in the Chattogram district of Bangladesh. Materials and Methods: This study was conducted on a dairy herd of 137 cattle in which two abortions were experienced...

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Main Authors: F. M. Yasir Hasib, Md. Sirazul Islam, Chandan Nath, Md. Moktadir Billah Reza, Md. Masuduzzaman, Sharmin Chowdhury
Format: Article
Language:English
Published: Network for the Veterinarians of Bangladesh 2025-07-01
Series:Veterinary Research Notes
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Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=241291
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author F. M. Yasir Hasib
Md. Sirazul Islam
Chandan Nath
Md. Moktadir Billah Reza
Md. Masuduzzaman
Sharmin Chowdhury
author_facet F. M. Yasir Hasib
Md. Sirazul Islam
Chandan Nath
Md. Moktadir Billah Reza
Md. Masuduzzaman
Sharmin Chowdhury
author_sort F. M. Yasir Hasib
collection DOAJ
description Objective: This study aimed to confirm probable causes of abortion with subsequent characterization of Brucella isolates from a dairy herd in the Chattogram district of Bangladesh. Materials and Methods: This study was conducted on a dairy herd of 137 cattle in which two abortions were experienced within days. Samples comprising aborted fetal tissues, uterine fluid, placental cotyledon, and whole blood were collected and processed to determine the cause of abortions. Serum samples (n = 137) were tested by Rose Bengal plate test (RBPT) and Indirect Enzyme Linked Immunosorbent Assay (I-ELISA). Isolation and identification were performed following standard bacteriological and molecular techniques. Results: A total of 91 samples (66.42%, 95% CI: 58.15–73.80) and 101 samples (73.72%, 95% CI: 65.75–80.40) tested positive by RBPT and I-ELISA, respectively. Both of the aborted samples were positive based on culture characteristics, RBPT, and I-ELISA tests, and were further confirmed as Brucella abortus through the AMOS-PCR assay. Partial genome sequencing of the two polymerase chain reaction-positive samples, followed by phylogenetic analysis, revealed close similarity with isolates from India, Pakistan, and China. Conclusion: The culling of brucellosis-positive cattle is the key to controlling and preventing brucellosis in herds. The findings highlighted the importance of brucellosis screening for optimizing both herd health and public health. [Vet. Res. Notes 2025; 5(7.000): 55-60]
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spelling doaj-art-f732642dc95a43b894614f3b057b527f2025-08-20T03:40:53ZengNetwork for the Veterinarians of BangladeshVeterinary Research Notes2790-22182025-07-0157556010.5455/vrn.2025.e57241291Brucella infection in a dairy herd of Chattogram, BangladeshF. M. Yasir Hasib0Md. Sirazul Islam1Chandan Nath2Md. Moktadir Billah Reza3Md. Masuduzzaman4Sharmin Chowdhury5Department of Pathology and Parasitology, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh Melbourne Veterinary School, Faculty of Science, University of Melbourne, Parkville, Australia Department of Microbiology and Veterinary Public Health, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh Department of Medicine and Surgery, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh Department of Pathology and Parasitology, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh Department of Pathology and Parasitology, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.Objective: This study aimed to confirm probable causes of abortion with subsequent characterization of Brucella isolates from a dairy herd in the Chattogram district of Bangladesh. Materials and Methods: This study was conducted on a dairy herd of 137 cattle in which two abortions were experienced within days. Samples comprising aborted fetal tissues, uterine fluid, placental cotyledon, and whole blood were collected and processed to determine the cause of abortions. Serum samples (n = 137) were tested by Rose Bengal plate test (RBPT) and Indirect Enzyme Linked Immunosorbent Assay (I-ELISA). Isolation and identification were performed following standard bacteriological and molecular techniques. Results: A total of 91 samples (66.42%, 95% CI: 58.15–73.80) and 101 samples (73.72%, 95% CI: 65.75–80.40) tested positive by RBPT and I-ELISA, respectively. Both of the aborted samples were positive based on culture characteristics, RBPT, and I-ELISA tests, and were further confirmed as Brucella abortus through the AMOS-PCR assay. Partial genome sequencing of the two polymerase chain reaction-positive samples, followed by phylogenetic analysis, revealed close similarity with isolates from India, Pakistan, and China. Conclusion: The culling of brucellosis-positive cattle is the key to controlling and preventing brucellosis in herds. The findings highlighted the importance of brucellosis screening for optimizing both herd health and public health. [Vet. Res. Notes 2025; 5(7.000): 55-60]http://www.ejmanager.com/fulltextpdf.php?mno=241291brucellosis; brucella abortus; chattogram; bangladesh; dairy herd
spellingShingle F. M. Yasir Hasib
Md. Sirazul Islam
Chandan Nath
Md. Moktadir Billah Reza
Md. Masuduzzaman
Sharmin Chowdhury
Brucella infection in a dairy herd of Chattogram, Bangladesh
Veterinary Research Notes
brucellosis; brucella abortus; chattogram; bangladesh; dairy herd
title Brucella infection in a dairy herd of Chattogram, Bangladesh
title_full Brucella infection in a dairy herd of Chattogram, Bangladesh
title_fullStr Brucella infection in a dairy herd of Chattogram, Bangladesh
title_full_unstemmed Brucella infection in a dairy herd of Chattogram, Bangladesh
title_short Brucella infection in a dairy herd of Chattogram, Bangladesh
title_sort brucella infection in a dairy herd of chattogram bangladesh
topic brucellosis; brucella abortus; chattogram; bangladesh; dairy herd
url http://www.ejmanager.com/fulltextpdf.php?mno=241291
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