Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman
Cerebral cavernous malformations (CCMs) are dilated blood vessels which can develop sporadically or in familial form and are the commonest malformations of blood vessels in the spinal cord and brain. The familial form is an autosomal dominant gene mutation disorder. This condition can be diagnosed w...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Case Reports in Radiology |
| Online Access: | http://dx.doi.org/10.1155/2021/9974776 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832568539183054848 |
|---|---|
| author | Klenam Dzefi-Tettey Emmanuel Kobina Mesi Edzie Philip Narteh Gorleku Henry Kusodzi Abdul Raman Asemah |
| author_facet | Klenam Dzefi-Tettey Emmanuel Kobina Mesi Edzie Philip Narteh Gorleku Henry Kusodzi Abdul Raman Asemah |
| author_sort | Klenam Dzefi-Tettey |
| collection | DOAJ |
| description | Cerebral cavernous malformations (CCMs) are dilated blood vessels which can develop sporadically or in familial form and are the commonest malformations of blood vessels in the spinal cord and brain. The familial form is an autosomal dominant gene mutation disorder. This condition can be diagnosed with magnetic resonance imaging (MRI) and computed tomography (CT) scan, but the modality of choice is MRI because of its high sensitivity. We report a case of a 73-year-old woman with an asymptomatic multiple familial cerebral cavernous malformation (FCCM) which was previously misdiagnosed as multiple cerebral metastases on CT scan. A brain MRI performed correctly diagnosed her condition as FCCM based on the typical MRI appearances. In order not to misdiagnose brain lesions like CCM on CT scan, for cerebral metastases in resource-poor settings, radiologists must recommend advanced imaging modalities like MRI for further evaluation, thereby avoiding unnecessary invasive surgical biopsies. |
| format | Article |
| id | doaj-art-f6e5cb0d80524ee1955268e83e193ae6 |
| institution | Kabale University |
| issn | 2090-6862 2090-6870 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Radiology |
| spelling | doaj-art-f6e5cb0d80524ee1955268e83e193ae62025-02-03T00:58:56ZengWileyCase Reports in Radiology2090-68622090-68702021-01-01202110.1155/2021/99747769974776Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old WomanKlenam Dzefi-Tettey0Emmanuel Kobina Mesi Edzie1Philip Narteh Gorleku2Henry Kusodzi3Abdul Raman Asemah4Department of Radiology, Korle Bu Teaching Hospital, 1 Guggisberg Avenue, Accra, GhanaDepartment of Medical Imaging, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, GhanaDepartment of Medical Imaging, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, GhanaDepartment of Medical Imaging, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, GhanaDepartment of Medical Imaging, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, GhanaCerebral cavernous malformations (CCMs) are dilated blood vessels which can develop sporadically or in familial form and are the commonest malformations of blood vessels in the spinal cord and brain. The familial form is an autosomal dominant gene mutation disorder. This condition can be diagnosed with magnetic resonance imaging (MRI) and computed tomography (CT) scan, but the modality of choice is MRI because of its high sensitivity. We report a case of a 73-year-old woman with an asymptomatic multiple familial cerebral cavernous malformation (FCCM) which was previously misdiagnosed as multiple cerebral metastases on CT scan. A brain MRI performed correctly diagnosed her condition as FCCM based on the typical MRI appearances. In order not to misdiagnose brain lesions like CCM on CT scan, for cerebral metastases in resource-poor settings, radiologists must recommend advanced imaging modalities like MRI for further evaluation, thereby avoiding unnecessary invasive surgical biopsies.http://dx.doi.org/10.1155/2021/9974776 |
| spellingShingle | Klenam Dzefi-Tettey Emmanuel Kobina Mesi Edzie Philip Narteh Gorleku Henry Kusodzi Abdul Raman Asemah Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman Case Reports in Radiology |
| title | Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman |
| title_full | Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman |
| title_fullStr | Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman |
| title_full_unstemmed | Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman |
| title_short | Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman |
| title_sort | asymptomatic familial multiple cerebral cavernous malformation in a 73 year old woman |
| url | http://dx.doi.org/10.1155/2021/9974776 |
| work_keys_str_mv | AT klenamdzefitettey asymptomaticfamilialmultiplecerebralcavernousmalformationina73yearoldwoman AT emmanuelkobinamesiedzie asymptomaticfamilialmultiplecerebralcavernousmalformationina73yearoldwoman AT philipnartehgorleku asymptomaticfamilialmultiplecerebralcavernousmalformationina73yearoldwoman AT henrykusodzi asymptomaticfamilialmultiplecerebralcavernousmalformationina73yearoldwoman AT abdulramanasemah asymptomaticfamilialmultiplecerebralcavernousmalformationina73yearoldwoman |