Myeloid ACAT1/SOAT1: a novel regulator of dyslipidemia and retinal neovascularization

Abstract Pathological retinal neovascularization (RNV) is a major cause of vision loss and blindness during ischemic retinopathies. Our investigations in the mouse model of oxygen-induced retinopathy (OIR) demonstrate a novel mechanism of pathological RNV and neurovascular injury. We show that OIR-i...

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Bibliographic Details
Main Authors: Syed A. H. Zaidi, Ruth B. Caldwell, Modesto A. Rojas
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Metabolic Health and Disease
Online Access:https://doi.org/10.1038/s44324-024-00046-x
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